ID F9X1L9_ZYMTI Unreviewed; 573 AA.
AC F9X1L9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=MYCGRDRAFT_107785 {ECO:0000313|EMBL:EGP91800.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP91800.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP91800.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- FUNCTION: Probable lipid hydrolase. {ECO:0000256|ARBA:ARBA00002682}.
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DR EMBL; CM001196; EGP91800.1; -; Genomic_DNA.
DR RefSeq; XP_003856824.1; XM_003856776.1.
DR AlphaFoldDB; F9X1L9; -.
DR STRING; 336722.F9X1L9; -.
DR EnsemblFungi; Mycgr3T107785; Mycgr3P107785; Mycgr3G107785.
DR GeneID; 13398382; -.
DR KEGG; ztr:MYCGRDRAFT_107785; -.
DR VEuPathDB; FungiDB:ZTRI_1.2075; -.
DR eggNOG; KOG2214; Eukaryota.
DR HOGENOM; CLU_009031_5_0_1; -.
DR InParanoid; F9X1L9; -.
DR OMA; GYGNIDQ; -.
DR OrthoDB; 154387at2759; -.
DR Proteomes; UP000008062; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF44; TRIACYLGLYCEROL LIPASE 3; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..381
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 540..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 63751 MW; 902235CEF5468692 CRC64;
MPKRPEGVPW PLAALIVVGN ILRSWISMIF TWYKKPRQED KLRTALQNAN TFPEWRRAAF
ALDHRKEAYN WRVNSVDKSY DYLRLEERRQ MLYRLRMKGD AVAVAELLRT GFLRNLFGIT
KLSLFRKTYI TTKDCIQAYI EETIACIRFV VESPPTITSR AGRLSAQDKL ELLENGQRMV
GSTALVMEGG SVFGLCHLGV MKALFEHNLL PRVIVGTATG AVMAALMSVQ TTEDLPAFLS
GRTIDLSAFS ESSLRAREKR MAEHQSFLHN WTATLWRRTS RILNTGFVLD PEVLAECIYA
NIGDTTFQEA FDKTGRVLNI IVTSPSDDIP NLLNYLTAST WLIRSAAMAS HLTNLDPNSE
IQLLKKDAHG NLVPIPVRPA SSHIGRARPR SDHPPLSRLR QQFNIDHFLV SQARPYLAPF
TLPSLPSIRP ADAPKSYLPK FLLPSVPFVA NTLLSALSSL NILPNSISRV RSDQSFPADT
LTFVPEFGAL DVKDLVMKNP TREDLVAWIG RGEKAVWPSL CAVQVRCAVE KALEGGLEAA
RRRGGRPGGG SGESGMRARG GGSRGGAFDW GQE
//
