ID F9XEZ3_ZYMTI Unreviewed; 923 AA.
AC F9XEZ3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=MYCGRDRAFT_44908 {ECO:0000313|EMBL:EGP85595.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP85595.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP85595.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; CM001202; EGP85595.1; -; Genomic_DNA.
DR RefSeq; XP_003850619.1; XM_003850571.1.
DR AlphaFoldDB; F9XEZ3; -.
DR STRING; 336722.F9XEZ3; -.
DR EnsemblFungi; Mycgr3T44908; Mycgr3P44908; Mycgr3G44908.
DR GeneID; 13401083; -.
DR KEGG; ztr:MYCGRDRAFT_44908; -.
DR eggNOG; KOG0220; Eukaryota.
DR HOGENOM; CLU_002472_7_3_1; -.
DR InParanoid; F9XEZ3; -.
DR OMA; KMTMLYK; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000008062; Chromosome 7.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062}.
FT DOMAIN 674..690
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..923
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 923 AA; 102802 MW; 5AAD5FAC2031BABD CRC64;
MATSHRPGTS IPFTTTYDTT ATGTRPGTSN PLTTTYEYTT GTESRPYTGH RSAGRPGTAR
PRTGVSTLGV ENQDIICAVS ESRGVSPSVG LAFLNLDTGE AVLSQFSDSQ TYVRTIHKLA
VFNPTTILAV SSSAQPKSKL FSIIEDGIQQ DLDSNVTLLD RRYWSETAGL DYIHHLAFPE
DVENLKTVLN GNYFAVCSFA AVLKFIEHGL SKIFPARSLR VKYEPSEGSM MIDLATIRSL
ELVQNLQNPK SKDCLFGQLN ETLTPMGARL LRSNILQPVT NPETLNKRYE AVEELSTKED
TFFAVRETLK PFLDADKTLT QLILSPVQIT VTTTEQSINN VIMLKQFVAL ISPVYEALTG
SRSDMLSTIR DICAPENIEP VQSLIAGAVN EDTTYAKKPL DLRNQRTYAV RSGVNGLLDV
ARQTYKESMT DALQHIDEVA QEHSLPLLTK FDNNRQFYLH LKAEELEDRN LPEIFINSYR
KKNIIECQTL DLVKLNQKIR DAHMEVLLMS DKAIRDLIDA VREHMPSLFK VCESIAMLDM
LAAFAHAVST CDYIRPQLNS TTLAIHSGRH PIREKIHTTQ KFVPNDVYAT QQTRFQIITG
ANMSGKSTYI RSVALITIMA QVGSFVPATY ASLPIIHHLF ARISIDDNIE ANVSSFAAEM
RETAFILHNI TPHSMAIVDE LGRGTSTRDG LAIAIAIAEA LVASRALVWF ATHFRDLASI
LAERNGVVNL HLAVDMSPED HRMEMLYRIA SGSEQVSHYG LALARIVPLP EDILPFAENV
SRTLEERGLA KQERSMGVVK ARRRKLMLNL KEHLVQAKES RMDDQALKKW LGDLQGEFVV
RMTALDEEAR EVMRREDEGG SVGRGEESED GRDGVEEEMM SMGYDEDEDD TGRATVGTGE
EQATFTHRTR AQTISSRQSS EMS
//
