ID F9XFX1_ZYMTI Unreviewed; 986 AA.
AC F9XFX1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Sodium/calcium exchanger membrane region domain-containing protein {ECO:0000259|Pfam:PF01699};
DE Flags: Fragment;
GN ORFNames=MYCGRDRAFT_20472 {ECO:0000313|EMBL:EGP86106.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP86106.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP86106.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
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DR EMBL; CM001202; EGP86106.1; -; Genomic_DNA.
DR RefSeq; XP_003851130.1; XM_003851082.1.
DR AlphaFoldDB; F9XFX1; -.
DR STRING; 336722.F9XFX1; -.
DR EnsemblFungi; Mycgr3T20472; Mycgr3P20472; Mycgr3G20472.
DR GeneID; 13397460; -.
DR KEGG; ztr:MYCGRDRAFT_20472; -.
DR eggNOG; KOG2399; Eukaryota.
DR HOGENOM; CLU_004979_2_0_1; -.
DR InParanoid; F9XFX1; -.
DR OMA; ARAHFHI; -.
DR OrthoDB; 5482417at2759; -.
DR Proteomes; UP000008062; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR PANTHER; PTHR12266:SF0; MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN; 1.
DR PANTHER; PTHR12266; NA+/CA2+ K+ INDEPENDENT EXCHANGER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 745..764
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 776..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..946
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 958..982
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..179
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 811..974
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 206..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..669
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGP86106.1"
FT NON_TER 986
FT /evidence="ECO:0000313|EMBL:EGP86106.1"
SQ SEQUENCE 986 AA; 107860 MW; 2B9D371C06792313 CRC64;
QCAYIRKHCP DDEAGFTAYL NLYYCQMPHL KPLAFIVLIS WLGLLFSTIG IAASDFFCID
LSTIAGILGM SESMAGVTFL AFGNGSPDVF STFAAMNTNS GSLAVGELFG AAGFITAVVA
GSMALIRPFH VAKKSFVRDV GFFIVAAAFS MLFLWDGKLR FWECAAMVIY YVVYVAFVVV
WHWWIGRRRR RREKDAAARG HFIDPSDEFG IDEEPYRDDP EETQTSRRPS LSRGASREDW
SALESGPADP REDSANVDDE EEARDRWMSE LASNMRLTRP TRSRKNTVTA VRPSLVGALE
FQAVLKSLQK SRNIQTIPMD SRRYSDDPVF TTAQQQEFMS SNADPASRPP YEVLVGGDRS
PQIVAHGPAD VTLESAPTGR ARAVSAMDGR TLQVGSNLQR LPPIPAEDDL IDGASVDSER
SRSRSRSLLD VPSTPNKAGS PDILVDHASP RQSVHPQRNH SRALSSDLLA PPGMAPAPRQ
GNDYFVAKPL SRTGTDDSPK DVATPIPRAG SLPKIQIPNQ RKSPSSSRAT SPFPAYRDYP
SPSMTASTRS PMSIKTPSIH LPPPMDSIGS PESIPADQSA EQEVPRRPTW LTRIWPYRIM
PPPGVMIAAL FPTIYHWHEK TWWEKCLGVV AAPSVFCLTV TLPVVENEKD NPEEDPIETA
RKDLSLESQR SKSTHAGPTL STTPISGIHS DYLLDVNDVH SHGGVAGHGS SATAATNAEH
HYRPHQLSAE PQAMPEPEPQ LWNRWLTILQ LFLAPIFIVL AIWVQAPDPL PPQWLIRPIL
ICLLVSLLLL VPILLTTTPT HRPRPYRIIL SLAGFVVSIA WISAIASQVV GALKALAVIL
NMSHAIMGLT IFAVGNSLGD LVADVTVAKL GYPVMALSAC FGGPMLNILL GVGLSGSYIM
LMGAEHRHEK HPKKGLKFHS YHIEVSKTLI VSGITLLVTL VGLLIAVPLN KWVLSRKIGW
ALIGLWTVST IFNVVIEVTG FLGDSS
//
