ID F9XMQ4_ZYMTI Unreviewed; 487 AA.
AC F9XMQ4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=3-dehydroquinate synthase {ECO:0000313|EMBL:EGP83658.1};
GN Name=MgCET1 {ECO:0000313|EMBL:EGP83658.1};
GN ORFNames=MYCGRDRAFT_76728 {ECO:0000313|EMBL:EGP83658.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP83658.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP83658.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; CM001206; EGP83658.1; -; Genomic_DNA.
DR RefSeq; XP_003848682.1; XM_003848634.1.
DR AlphaFoldDB; F9XMQ4; -.
DR STRING; 336722.F9XMQ4; -.
DR EnsemblFungi; Mycgr3T76728; Mycgr3P76728; Mycgr3G76728.
DR GeneID; 13396317; -.
DR KEGG; ztr:MYCGRDRAFT_76728; -.
DR VEuPathDB; FungiDB:ZTRI_11.123; -.
DR eggNOG; KOG0692; Eukaryota.
DR HOGENOM; CLU_001201_0_4_1; -.
DR InParanoid; F9XMQ4; -.
DR OMA; HIRIPTT; -.
DR OrthoDB; 453at2759; -.
DR Proteomes; UP000008062; Chromosome 11.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR CDD; cd08199; EEVS; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR030960; DHQS/DOIS.
DR InterPro; IPR035872; EEVS-like.
DR PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR43622:SF1; 3-DEHYDROQUINATE SYNTHASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01761; DHQ_synthase; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062}.
FT DOMAIN 86..341
FT /note="3-dehydroquinate synthase"
FT /evidence="ECO:0000259|Pfam:PF01761"
FT REGION 433..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 53699 MW; 3262E90B88DF8B2B CRC64;
MSDMSATVAE TPKGFHVEGY EKIEYDFTFL DYVFDVKKDD LAKCYERWGR VLAVMDANIF
EQYGEDLQQY CDHYKLDLSI HKTMIGEKAK SIDTFLSIVD SMTKFGIYRK EPVLVIGGGL
VTDVAGFACA AYRRNTNFIR IPTTVIGLID ASVSIKVGVN YGNYKNRLGA YHAPIHTFLD
FTFLRSLPTA QIRNGFAELI KISSCAHLPT FDLLDKYCEE IIKTGFGRTD DATAEVKEAC
DKINRAGIHE MLKLETPNLH EIGLDRVIAY GHTWSPLHEL VPKVPLRHGH AISIDMAFSA
TLAHQRGNLP QADYERLLKL FSRCGLSMDH PDFNEEILAQ ATAAILKTRD GKLRAAVPSP
LGSCEFFNDV TEKEMNDALR KHKEVCKTYP RNGEGLEAFV DASDTGYTKN KAPVEKKLSN
GLKKLNVLND DVSNGTNGFS PEKAEGLANG ALNGSTKSIN GNGHANGHAN GNGHANGHAN
GDHGDCC
//
