ID F9YQ80_CAPCC Unreviewed; 308 AA.
AC F9YQ80;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase {ECO:0000313|EMBL:AEK23499.1};
DE EC=2.3.1.129 {ECO:0000313|EMBL:AEK23499.1};
GN OrderedLocusNames=Ccan_13830 {ECO:0000313|EMBL:AEK23499.1};
OS Capnocytophaga canimorsus (strain 5).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=860228 {ECO:0000313|EMBL:AEK23499.1, ECO:0000313|Proteomes:UP000008895};
RN [1] {ECO:0000313|EMBL:AEK23499.1, ECO:0000313|Proteomes:UP000008895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5 {ECO:0000313|Proteomes:UP000008895};
RX PubMed=21914877; DOI=10.1128/JB.05853-11;
RA Manfredi P., Pagni M., Cornelis G.R.;
RT "Complete genome sequence of the dog commensal and human pathogen
RT Capnocytophaga canimorsus strain 5.";
RL J. Bacteriol. 193:5558-5559(2011).
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DR EMBL; CP002113; AEK23499.1; -; Genomic_DNA.
DR RefSeq; WP_013997487.1; NC_015846.1.
DR AlphaFoldDB; F9YQ80; -.
DR STRING; 860228.Ccan_13830; -.
DR KEGG; ccm:Ccan_13830; -.
DR eggNOG; COG1044; Bacteria.
DR HOGENOM; CLU_049865_0_2_10; -.
DR OrthoDB; 9784739at2; -.
DR Proteomes; UP000008895; Chromosome.
DR GO; GO:0008780; F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016410; F:N-acyltransferase activity; IEA:InterPro.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd03352; LbH_LpxD; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR Gene3D; 3.40.1390.10; MurE/MurF, N-terminal domain; 1.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR007691; LpxD.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR InterPro; IPR020573; UDP_GlcNAc_AcTrfase_non-rep.
DR NCBIfam; TIGR01853; lipid_A_lpxD; 1.
DR PANTHER; PTHR43378; UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR43378:SF2; UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00132; Hexapep; 2.
DR Pfam; PF04613; LpxD; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:AEK23499.1};
KW Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000008895};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEK23499.1}.
FT DOMAIN 27..91
FT /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine N-
FT acyltransferase non-repeat region"
FT /evidence="ECO:0000259|Pfam:PF04613"
SQ SEQUENCE 308 AA; 33585 MW; BD588A1B7686E6E2 CRC64;
MKFPQTYTLQ QIATIIDADF VGSPEFPVLG MNEIHVVEEG DIVFVDHPKY YDKALQSKAT
IVLINKRVVC PQGKALLISD DPFRDFNKLT EFFKPFAKSE NLISKTAKIG SNTVIQPGAF
IGNHVIIGKN CFIHANVSIY DDCIIGDNVT IHAGTVLGAD AFYYKKRPEG FDKLKSGGRV
VIEDDVDLGA LCTIDRGVTG DTTIKKGTKI DNQVHIGHDT VIGERCLIAS QTGIAGCVVI
ENEVTIWGQV GVASSITIGS KSIILAQSGI SKSLEGGQTY FGYPAEEARK KYKELSTLRM
MVSQYGKK
//
