ID F9ZF56_9PROT Unreviewed; 738 AA.
AC F9ZF56;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=NAL212_0824 {ECO:0000313|EMBL:ADZ25756.1};
OS Nitrosomonas sp. AL212.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=153948 {ECO:0000313|EMBL:ADZ25756.1, ECO:0000313|Proteomes:UP000001629};
RN [1] {ECO:0000313|EMBL:ADZ25756.1, ECO:0000313|Proteomes:UP000001629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL212 {ECO:0000313|EMBL:ADZ25756.1,
RC ECO:0000313|Proteomes:UP000001629};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Suwa Y., Klotz M.G.,
RA Bollmann A., Stein L.Y., Laanbroek H.J., Arp D.J., Norton J.M., Woyke T.;
RT "Complete sequence of chromosome of Nitrosomonas sp. AL212.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
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DR EMBL; CP002552; ADZ25756.1; -; Genomic_DNA.
DR AlphaFoldDB; F9ZF56; -.
DR STRING; 153948.NAL212_0824; -.
DR KEGG; nit:NAL212_0824; -.
DR eggNOG; COG1452; Bacteria.
DR HOGENOM; CLU_009039_0_0_4; -.
DR Proteomes; UP000001629; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|HAMAP-Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000001629};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 23..738
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5009012541"
FT DOMAIN 46..116
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 285..656
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 738 AA; 83328 MW; E41A45A2ED7BA0FA CRC64;
MKRIIRSISF LILLGLPLTC WSNESSAVTL ESEQKSVIKP QKKPVLIEAD RITGYYKQEI
EATGDAMLHH GDNVLTADRM KYYQQTEDAE VEGNVRLERP NDILQGQQLE INLKTEVGHL
TEPRYSMKEG KGRGAGDILL FEGKDNYRIK DTNYTACPEG NHDWYLRAKE LEIDNKKEVG
TARHVSVVFK DVPLLYSPWL DFSYSGKRKS GLLAPVAGYN VRTGFDVGLP VYLNIAPNID
ATITPRIMTE RGFLLSNEFR YIGNNNMNGH LQFDILPQDI DRNRTRWGIL FTHTQNLGKG
WQGFMNYNQV SDDRYFRELT PNLAQTSLVN LSQQGGVNYN GRLGTDGVLN FTGFAQRFQT
IQDPFALIVS PYERLPHFAV NAAKYNVGGK LDFELQSSWT NFYHPTLVDG NRTIFYPSVS
APLRNEYGYI TPKFGLHYTH YNLAAPVDTK GENVDRTVPI VSLDSGIAFD RQLNLGDRNI
IQTLEPRLFY VYAPYRNQDY LPNFDSAVND FSFAQMLTEN KFSGGDRIND ANRAVAALTS
RFVDKDTGVE FLRLAVGQMV NFTDPRIQLP LPQVTSGRSD FIAAISGRLT QDISTDSNVQ
IDQSKGVIEK IRSGISYQPE PGKVLNFGYR FTRDVREQVD TSIEQVDTSM QWPIYGNLRG
VTRVNYSLND DKILAGLAGL EYNSCCWALR VVLQRLTTAT QTTTTAFFLQ LELKGLMGLG
NNPLQVLQQT IPGYTSVH
//
