ID F9ZSI9_ACICS Unreviewed; 763 AA.
AC F9ZSI9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=NADH-ubiquinone oxidoreductase chain G {ECO:0000313|EMBL:AEK59220.1};
GN OrderedLocusNames=Atc_2573 {ECO:0000313|EMBL:AEK59220.1};
OS Acidithiobacillus caldus (strain SM-1).
OC Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=990288 {ECO:0000313|EMBL:AEK59220.1, ECO:0000313|Proteomes:UP000006135};
RN [1] {ECO:0000313|EMBL:AEK59220.1, ECO:0000313|Proteomes:UP000006135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM-1 {ECO:0000313|EMBL:AEK59220.1,
RC ECO:0000313|Proteomes:UP000006135};
RX PubMed=21703548; DOI=10.1016/j.jgg.2011.04.006;
RA You X.Y., Guo X., Zheng H.J., Zhang M.J., Liu L.J., Zhu Y.Q., Zhu B.,
RA Wang S.Y., Zhao G.P., Poetsch A., Jiang C.Y., Liu S.J.;
RT "Unraveling the Acidithiobacillus caldus complete genome and its central
RT metabolisms for carbon assimilation.";
RL J. Genet. Genomics 38:243-252(2011).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404}.
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DR EMBL; CP002573; AEK59220.1; -; Genomic_DNA.
DR RefSeq; WP_014003491.1; NC_015850.1.
DR AlphaFoldDB; F9ZSI9; -.
DR STRING; 990288.Atc_2573; -.
DR GeneID; 69613377; -.
DR KEGG; acu:Atc_2573; -.
DR HOGENOM; CLU_000422_11_5_6; -.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000006135; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.200.210; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00641; COMPLEX1_75K_1; 1.
DR PROSITE; PS00642; COMPLEX1_75K_2; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000006135};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 1..86
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 86..125
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 224..280
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 763 AA; 84109 MW; 3135F9A6FFA0082E CRC64;
MTAHFYLDGR AIPFVAGQNV LEALLAMGRD RDVPYFCYHP ALGSLGACRQ CAVKFYPHDD
RHPPRVMMAC LLPASPGLQL VTAEADVERE HAAISELLMR NHPHDCPVCD EGGQCHLQDM
TVRAGHRLRT YENRKRTFRS QQLGPLIRQE MNRCITCYRC VRFYQDIAGG EDFGVFGSRD
RVFFGRLQDG ALESPFAGNL AEICPTGVFT DKVYHANYLR PWDLETAPSV CPHCNLGCNT
APGAARGRLR RVRQRPHPDI NPHFLCDRGR YGFRHTAHRQ RPWTNQLRGR DVDSDATLDH
LADILAQGQT AFLGSPRADI LANLAWLALA DAYGAPFAAF SDPWQEALAR EILALPQAPS
LAELAKAERI LILGQALELS PSLRLPVQAA VRAGAHLTLA SVLPTALDKH GQVQRLRPDG
FVDAAGAWCR ALPSGKRAVI LASADALGPA GVHVVRRLQE DLPPGTGVIV AHTAPNLGGA
AFFATDGQSA RLREAVAIGR CRHLLALAAD PLGEDGDAPF WRQRPPELQI SLLDHLPTTT
YGEADLRLPM AATAERDGVF LNYEGRFQAF AKVYQPAREQ RQWDPSHSAF PLPAGGMREA
MALWEPYTLA EALAQRGDRL ERFRQRFAFY RHYLCPELPA PGDPGAFLPD GLRARFRIGI
VPVPHSGSGR WWLSANHWYG DEAQARFALE LQSLAPVPGV RLAPGQTEAR ALLLTSRDGQ
VRRFPVIEVE GMATDVLALD PAQLSDLGYH PGERIDAREE VAP
//
