ID   FLAC_VIBPA              Reviewed;         384 AA.
AC   Q56712;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2003, sequence version 2.
DT   27-MAR-2024, entry version 127.
DE   RecName: Full=Polar flagellin C;
GN   Name=flaC; OrderedLocusNames=VP0788;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BB22;
RX   PubMed=7883718; DOI=10.1128/jb.177.6.1595-1609.1995;
RA   McCarter L.L.;
RT   "Genetic and molecular characterization of the polar flagellum of Vibrio
RT   parahaemolyticus.";
RL   J. Bacteriol. 177:1595-1609(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella. FlaC is not essential for polar
CC       flagellar synthesis and swimming motility. Homomer of FlaC is not able
CC       to form a functional filament.
CC   -!- SUBUNIT: Heteromer of multiple flagellin subunits including FlaA,
CC       FlaB/D, FlaC, FlaE and FlaF. Homomer of FlaC is not able to form a
CC       functional filament.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- MISCELLANEOUS: V.parahaemolyticus possesses two flagellar systems: a
CC       single polar flagellum propels the bacterium in liquid (swimming),
CC       while multiple lateral (peritrichous) flagella move the bacterium over
CC       surfaces (swarming). The polar flagellum is synthesized constitutively
CC       but lateral flagella are produced only under conditions in which the
CC       polar flagellum is not functional.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; U12817; AAD10271.1; -; Genomic_DNA.
DR   EMBL; BA000031; BAC59051.1; -; Genomic_DNA.
DR   RefSeq; NP_797167.1; NC_004603.1.
DR   RefSeq; WP_005462278.1; NC_004603.1.
DR   AlphaFoldDB; Q56712; -.
DR   SMR; Q56712; -.
DR   GeneID; 1188285; -.
DR   KEGG; vpa:VP0788; -.
DR   PATRIC; fig|223926.6.peg.752; -.
DR   eggNOG; COG1344; Bacteria.
DR   HOGENOM; CLU_011142_7_1_6; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 2.60.40.4390; -; 1.
DR   Gene3D; 6.10.280.190; -; 1.
DR   Gene3D; 1.20.1330.10; f41 fragment of flagellin, N-terminal domain; 1.
DR   Gene3D; 6.10.10.10; Flagellar export chaperone, C-terminal domain; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR001029; Flagellin_N.
DR   PANTHER; PTHR42792; FLAGELLIN; 1.
DR   PANTHER; PTHR42792:SF2; FLAGELLIN; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   PRINTS; PR00207; FLAGELLIN.
DR   SUPFAM; SSF64518; Phase 1 flagellin; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..384
FT                   /note="Polar flagellin C"
FT                   /id="PRO_0000182655"
FT   COILED          317..347
FT                   /evidence="ECO:0000255"
FT   CONFLICT        277
FT                   /note="E -> Q (in Ref. 1; AAD10271)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   384 AA;  40812 MW;  C239846EC9A8558A CRC64;
     MAVTVSTNVS AMTAQRYLNK ATNELNTSME RLSSGHKINS AKDDAAGLQI SNRLTAQSRG
     LDVAMRNAND GISIAQTAEG AMNEATSVMQ RMRDLAIQSS NGTNSPAERQ AINEESMALV
     DELNRIAETT SFGGRRLLNG SFGEAAFQIG ASSGEAMIMG LTSIRADDTR MGGVTFFSEV
     GKGKDWGVDP TKADLKITLP GMGEDEDGNV DDLEININAK AGDDIEELAT YINGQSDMIN
     ASVSEDGKLQ IFVAHPNVQG DISISGGLAS ELGLSDEPVR TSVQDIDMTT VQGSQNAISV
     LDSALKYVDS QRADLGAKQN RLSHSINNLA NIQENVDASN SRIKDTDFAK ETTQMTKAQI
     LQQAGTSILA QAKQLPNSAM SLLQ
//