ID FOXD4_RAT Reviewed; 101 AA.
AC Q63249;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 27-MAR-2024, entry version 128.
DE RecName: Full=Forkhead box protein D4;
DE AltName: Full=Forkhead-related protein FKHL9;
DE AltName: Full=Forkhead-related transcription factor 5;
DE Short=FREAC-5;
DE AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 6;
DE Short=HFH-6;
DE Flags: Fragment;
GN Name=Foxd4; Synonyms=Fkhl9, Freac5, Hfh6;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Sprague-Dawley;
RX PubMed=7683413; DOI=10.1073/pnas.90.9.3948;
RA Clevidence D.E., Overdier D.G., Tao W., Qian X., Pani L., Lai E.,
RA Costa R.H.;
RT "Identification of nine tissue-specific transcription factors of the
RT hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.";
RL Proc. Natl. Acad. Sci. U.S.A. 90:3948-3952(1993).
CC -!- SUBCELLULAR LOCATION: Nucleus.
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DR EMBL; L13206; AAA41322.1; -; mRNA.
DR PIR; I60920; I60920.
DR AlphaFoldDB; Q63249; -.
DR SMR; Q63249; -.
DR PhosphoSitePlus; Q63249; -.
DR UCSC; RGD:621716; rat.
DR AGR; RGD:621716; -.
DR RGD; 621716; Foxd4.
DR InParanoid; Q63249; -.
DR PhylomeDB; Q63249; -.
DR TreeFam; TF316127; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20048; FH_FOXD4-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF350; FORKHEAD BOX PROTEIN D4-LIKE 3-RELATED; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN <1..>101
FT /note="Forkhead box protein D4"
FT /id="PRO_0000091823"
FT DNA_BIND 2..93
FT /note="Fork-head"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00089"
FT NON_TER 1
FT NON_TER 101
SQ SEQUENCE 101 AA; 11799 MW; 127DA134700CA228 CRC64;
PAKPPYSYIA LITMAILQSP HKRLTLSGIC AFISGRFPYY RRKFPAWQNS IRHNLSLNDC
FVKIPREPGH PGKGNYWSLD PASQDMFDNG SFLRRRKRFK R
//
