ID FTSL_PSEAE Reviewed; 97 AA.
AC Q9HVZ6;
DT 14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE RecName: Full=Cell division protein FtsL {ECO:0000255|HAMAP-Rule:MF_00910};
GN Name=ftsL {ECO:0000255|HAMAP-Rule:MF_00910}; OrderedLocusNames=PA4419;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Essential cell division protein. May link together the
CC upstream cell division proteins, which are predominantly cytoplasmic,
CC with the downstream cell division proteins, which are predominantly
CC periplasmic. {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBUNIT: Part of a complex composed of FtsB, FtsL and FtsQ.
CC {ECO:0000255|HAMAP-Rule:MF_00910}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00910}; Single-pass type II membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_00910}. Note=Localizes to the division
CC septum where it forms a ring structure. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
CC -!- SIMILARITY: Belongs to the FtsL family. {ECO:0000255|HAMAP-
CC Rule:MF_00910}.
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DR EMBL; AE004091; AAG07807.1; -; Genomic_DNA.
DR PIR; D83095; D83095.
DR RefSeq; NP_253109.1; NC_002516.2.
DR RefSeq; WP_003094142.1; NZ_QZGE01000004.1.
DR PDB; 8BH1; EM; 3.80 A; D=1-97.
DR PDBsum; 8BH1; -.
DR AlphaFoldDB; Q9HVZ6; -.
DR EMDB; EMD-16042; -.
DR SMR; Q9HVZ6; -.
DR STRING; 208964.PA4419; -.
DR PaxDb; 208964-PA4419; -.
DR DNASU; 881233; -.
DR GeneID; 881233; -.
DR KEGG; pae:PA4419; -.
DR PATRIC; fig|208964.12.peg.4628; -.
DR PseudoCAP; PA4419; -.
DR HOGENOM; CLU_156524_1_3_6; -.
DR InParanoid; Q9HVZ6; -.
DR OrthoDB; 5298556at2; -.
DR PhylomeDB; Q9HVZ6; -.
DR BioCyc; PAER208964:G1FZ6-4506-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR HAMAP; MF_00910; FtsL; 1.
DR InterPro; IPR011922; Cell_div_FtsL.
DR NCBIfam; TIGR02209; ftsL_broad; 1.
DR PANTHER; PTHR37479; CELL DIVISION PROTEIN FTSL; 1.
DR PANTHER; PTHR37479:SF1; CELL DIVISION PROTEIN FTSL; 1.
DR Pfam; PF04999; FtsL; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell cycle; Cell division; Cell inner membrane;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..97
FT /note="Cell division protein FtsL"
FT /id="PRO_0000414565"
FT TOPO_DOM 1..11
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
FT TOPO_DOM 33..97
FT /note="Periplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00910"
SQ SEQUENCE 97 AA; 11138 MW; 7704D6F41E29499F CRC64;
MSRLFVKRLP TGSFLMLLLY IGLLLSAIAV AYSTYWNRQL LNSLYSELSV RDKAQAEWGR
LILEQSTWTA HSRIESLAVE QLRMRVPDPA EVRMVAP
//
