ID G0GEP8_SPITZ Unreviewed; 427 AA.
AC G0GEP8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Peptidase M28 {ECO:0000313|EMBL:AEJ60736.1};
GN OrderedLocusNames=Spith_0453 {ECO:0000313|EMBL:AEJ60736.1};
OS Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC Spirochaeta.
OX NCBI_TaxID=869211 {ECO:0000313|EMBL:AEJ60736.1, ECO:0000313|Proteomes:UP000007254};
RN [1] {ECO:0000313|EMBL:AEJ60736.1, ECO:0000313|Proteomes:UP000007254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700085 / DSM 6578 / Z-1203
RC {ECO:0000313|Proteomes:UP000007254};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikailova N., Pagani I.,
RA Chertkov O., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S.,
RA Merkhoffer B., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Spirochaeta thermophila DSM 6578.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002903; AEJ60736.1; -; Genomic_DNA.
DR RefSeq; WP_014624134.1; NC_017583.1.
DR AlphaFoldDB; G0GEP8; -.
DR STRING; 869211.Spith_0453; -.
DR KEGG; stq:Spith_0453; -.
DR HOGENOM; CLU_578593_0_0_12; -.
DR OrthoDB; 9762302at2; -.
DR Proteomes; UP000007254; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007254};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..386
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT REGION 405..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 47182 MW; CEA0AEB0D7148181 CRC64;
MASRVIFERI EVRRIKALLE EWIRRFPSRL AGTPGCDEAG AAIEEAFRQA GTKAWRESFV
CSPDAFMGYH VYVFLLYAVG VVFLAYGWPV VAGLCFLVGL AMDLGEFVLF LPVVDRFFPR
RVCRNVIAEI PAAGEERLVV YVCAHHDAAR ELPYLKRRQV LYPLKVLGGE AFTLGAALCA
LGVGLGWWTL GPGWVIFFVL GIPFLFQRAT FVFRHGVPGA GDNLVACAML VELARLYARR
PPQYVTLRLV SFDAEESGLR GSAAFVRRHR DELQGTPVVV LNIDSIYRRE DLQILVSDIN
GLLLLSGELA SRVARWAEEA GVGLPVRRMT FGGGGTDAAS FARAGLPTIS LIGIANRMIR
RRLVYHTMAD LPPAVEDEAV RDLMKALLVG LRRLDEEGYA VYKEGKTVPK GGRDEGATRD
RRGGVRG
//
