ID G0IWG3_CYCMS Unreviewed; 541 AA.
AC G0IWG3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Peptidase S8 and S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:AEL27957.1};
GN OrderedLocusNames=Cycma_4254 {ECO:0000313|EMBL:AEL27957.1};
OS Cyclobacterium marinum (strain ATCC 25205 / DSM 745 / LMG 13164 / NCIMB
OS 1802) (Flectobacillus marinus).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Cyclobacterium.
OX NCBI_TaxID=880070 {ECO:0000313|EMBL:AEL27957.1, ECO:0000313|Proteomes:UP000001635};
RN [1] {ECO:0000313|Proteomes:UP000001635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25205 / DSM 745 / LMG 13164 / NCIMB 1802
RC {ECO:0000313|Proteomes:UP000001635};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Schuetze A.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Cyclobacterium marinum DSM 745.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CP002955; AEL27957.1; -; Genomic_DNA.
DR RefSeq; WP_014022241.1; NC_015914.1.
DR AlphaFoldDB; G0IWG3; -.
DR STRING; 880070.Cycma_4254; -.
DR KEGG; cmr:Cycma_4254; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_026626_0_0_10; -.
DR OrthoDB; 9792152at2; -.
DR Proteomes; UP000001635; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07493; Peptidases_S8_9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR017317; Pept_S8_subtilisin_bacteroid-2.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR026444; Secre_tail.
DR NCBIfam; TIGR04183; Por_Secre_tail; 1.
DR PANTHER; PTHR43806:SF61; EGF-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF18962; Por_Secre_tail; 1.
DR PIRSF; PIRSF037903; Subtilisin_rel_GFO_2223; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000001635};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 165..439
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 465..537
FT /note="Secretion system C-terminal sorting"
FT /evidence="ECO:0000259|Pfam:PF18962"
FT ACT_SITE 174
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 215
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 393
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 541 AA; 59237 MW; C7AD6A0CE2A2C748 CRC64;
MVKFSTAIVL LFWLTIVNGL AQDRYAVHYK YKPNGVFSES LLSEKSITRR SRDNVLLDST
DLPVATKYIE AIRPYVNRFI YHSKWLNASI IQASEEAIKD ISSLDFVNEV NLVAKGEGGT
LERSTKNYKA KKKKKGNSSA TAPSDFEFQN SILGISAMHE AGYTGEGVFV AIFDAGFLNV
DKIPAFDHLF AEQKIYATKD FVVPDSDNVY RADTHGTGTL SLMAAYDPEN LIAGAYGASY
ILCITEDVDS EYRIEEYNWV KAAEYADSLG VDLINSSLGY NYFDDEGMNY SKEDLDGQTA
IITKGANMAA EKGILVVSSA GNEGNISWKT ITVPSDAKNI LSVGAINSNL NKAGFSSIGP
SADNRIKPEL VAYGSGVTLW RQEEGTSSSS GTSFSAPQVA ALAAGLREAN PNWTNDKLRE
QILLSGSQFT QPDNELGYGV PDFTRAMFGK LIEDGEPEGE STTRVYPNPL TKDELLIEFG
TSINCTMKLF ASDGKLVSEL ELERSKSNFP YSASMEVLNP GIYLVELQDD SSVSTVKLWK
K
//
