ID G0J5U6_CYCMS Unreviewed; 727 AA.
AC G0J5U6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Peptidase S9B dipeptidylpeptidase IV domain protein {ECO:0000313|EMBL:AEL25397.1};
GN OrderedLocusNames=Cycma_1643 {ECO:0000313|EMBL:AEL25397.1};
OS Cyclobacterium marinum (strain ATCC 25205 / DSM 745 / LMG 13164 / NCIMB
OS 1802) (Flectobacillus marinus).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Cyclobacterium.
OX NCBI_TaxID=880070 {ECO:0000313|EMBL:AEL25397.1, ECO:0000313|Proteomes:UP000001635};
RN [1] {ECO:0000313|Proteomes:UP000001635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25205 / DSM 745 / LMG 13164 / NCIMB 1802
RC {ECO:0000313|Proteomes:UP000001635};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Chertkov O.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Schuetze A.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Cyclobacterium marinum DSM 745.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
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DR EMBL; CP002955; AEL25397.1; -; Genomic_DNA.
DR RefSeq; WP_014019692.1; NC_015914.1.
DR AlphaFoldDB; G0J5U6; -.
DR STRING; 880070.Cycma_1643; -.
DR KEGG; cmr:Cycma_1643; -.
DR eggNOG; COG0823; Bacteria.
DR eggNOG; COG1506; Bacteria.
DR HOGENOM; CLU_006105_2_0_10; -.
DR OrthoDB; 9812921at2; -.
DR Proteomes; UP000001635; Chromosome.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF200; DIPEPTIDYL PEPTIDASE FAMILY MEMBER 2; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001635};
KW Signal {ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..727
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003400798"
FT DOMAIN 101..442
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 530..726
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 727 AA; 83024 MW; F8C96088A1049AA7 CRC64;
MKRYYKIQAF LVYVLLFTTS GLAQDNKKLT LEAVIKDQVF APKTVQGINW MKDGKYYSSL
KMVAGFPQVV RINVATGEES EVLIDGRELG LNFSNYAFNP EESMALLTSE VEPIYRRSTK
AIYHLLDLKT GSLKELENGD KISYATLSPD NQKVAYVKEN NLYYLDLKTN NKVQVTRDGA
KNAIINGAAD WVYEEEFSMS KAFFWSNDGN KLAYIRFDER EVPVFNMQKW GALYPEDEHF
KYPKAGEKNA IVSIQIYNLE KEQTQTVDTG ADTDIYLPRM YWAEDNNTLA VIRLNRLQNQ
MDILFADSQT GESKNILSET SDTYVDMDYN DNFLFLPNGE GFIGTSEKDG FKHVYQYDLE
GKLIRQITKG EWEVTELVAV DSKAGKVYYV STEQSPLERH FYSINLNGKK KKLLTPQEGT
HSINMSPDQQ YYIDAYSTVT QPLQVVLSDK EGKEIKVLED NNALQEKMKE YAYLPKEFFD
FKTIDGTSLN GYMIKPVTFD PSKTYPVLMY VYGGPGSQNV MNNWGSTRDW WHQHLAAEGY
IVVGIDNRGT GGRGRDFKHS TYNQLGKLET EDQIAGAKYL AELPYVDASR IGIWGWSYGG
YMSSLALMIG NETFKTAMAV APVTSWRYYD TIYTERFLQT PQLNPAGYDD FSPINHVNKL
YGNFLLVHGT GDDNVHFQNS VALVDALIAA DKQFDSFYYP NRNHGIHGGN TTWHLYKMLT
NYVKDKL
//
