ID   G0L382_ZOBGA            Unreviewed;       799 AA.
AC   G0L382;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE            EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN   Name=rhaB {ECO:0000313|EMBL:CAZ95279.1};
GN   OrderedLocusNames=zobellia_1223 {ECO:0000313|EMBL:CAZ95279.1};
OS   Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 /
OS   NCIMB 13871 / Dsij).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Zobellia.
OX   NCBI_TaxID=63186 {ECO:0000313|EMBL:CAZ95279.1, ECO:0000313|Proteomes:UP000008898};
RN   [1] {ECO:0000313|Proteomes:UP000008898}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC   {ECO:0000313|Proteomes:UP000008898};
RG   Genoscope - CEA;
RT   "Complete genome sequence of Zobellia galactanivorans Dsij.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CAZ95279.1, ECO:0000313|Proteomes:UP000008898}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC   {ECO:0000313|Proteomes:UP000008898};
RX   PubMed=22513138; DOI=10.1111/j.1462-2920.2012.02751.x;
RA   Thomas F., Barbeyron T., Tonon T., Genicot S., Czjzek M., Michel G.;
RT   "Characterization of the first alginolytic operons in a marine bacterium:
RT   from their emergence in marine Flavobacteriia to their independent
RT   transfers to marine Proteobacteria and human gut Bacteroides.";
RL   Environ. Microbiol. 14:2379-2394(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC         in alpha-L-rhamnosides.; EC=3.2.1.40;
CC         Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR   EMBL; FP476056; CAZ95279.1; -; Genomic_DNA.
DR   RefSeq; WP_013992588.1; NC_015844.1.
DR   AlphaFoldDB; G0L382; -.
DR   STRING; 63186.ZOBELLIA_1223; -.
DR   KEGG; zga:ZOBELLIA_1223; -.
DR   PATRIC; fig|63186.3.peg.1206; -.
DR   HOGENOM; CLU_009782_0_0_10; -.
DR   OrthoDB; 9815108at2; -.
DR   Proteomes; UP000008898; Chromosome.
DR   GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR035396; Bac_rhamnosid6H.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR34987:SF2; B, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05040)-RELATED; 1.
DR   PANTHER; PTHR34987; C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED; 1.
DR   Pfam; PF17389; Bac_rhamnosid6H; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:CAZ95279.1};
KW   Hydrolase {ECO:0000313|EMBL:CAZ95279.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008898}.
FT   DOMAIN          385..718
FT                   /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT                   /evidence="ECO:0000259|Pfam:PF17389"
SQ   SEQUENCE   799 AA;  91698 MW;  A3490C7A766E98BF CRC64;
     MNLFLSIFLF CSPLFLLGQS ELNYPELLYP PQAIKANWVS HPDIQGGEDR IVLFRNEWMV
     DDPSEAFIIN ISADNHYFLY VNGNLVTHGP QLSDIRHWKY ETIDLKTYLK TGKNLIAIKV
     VNYGKRRFYG MQSIFTSLMV NGATENAKVL NTSGTDDGWK CSIDDSYRAL EVNWRGGGPK
     SIVGGFYANN PTDFVDKNHY PTDWEQPDFD DSDWVDTQFF EGASSMGGSM AYLLEPRNLP
     LLTWEKEGIG HTVRTSDIDV SEFPVSGKTV VPEHKKIRFL IDQKYVTNGF PELIFSKGKN
     AHIKIKYAEN LFGPKNTKGD RNIIKGKELL GYYDHVVSNG KERQKFTPNW MRTFRFVEFE
     IETKGQELVL DSFSNYRSRT HIPSIARFSS NNETYNAIFD ICKRTVDICT QDYFLSDAYY
     ETMQYVGDTK IHALLWQAMS GNLAHTKNAI EQFHRSRDAD GNILGAYPLR STFIYPTYSL
     VWVDMVYDYY QLTNDTDFIN TYKDGIIHTL AGFEKNMNEL NLVNETQYRY FVDWYTGPNN
     GGGTATKNNG KNSAVVSLHY VHALQNAARL FKAIGDKHTA DTYLDRATAI KSSVYKLCFD
     PNKNIFAERP DKTVYDQHTN IMAVLTDAIA ESEQKALLSN ILNDPKLLQA TYYYRYYLFE
     AIKKVGAPEL FDLAQRPWQA MIDNHMTTTL ERFESDKKPT RSEVHPWSAS PAYFYFNYLA
     GIKSVKNDFQ EIEIAPVFGI LEDMEGLLPT SKGNILFHLK KIRSKLSAEI IVPKEMSGEL
     VWNEKHIPLK HGQHTYILK
//