ID G0L3D2_ZOBGA Unreviewed; 248 AA.
AC G0L3D2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:CAZ95366.1};
DE EC=4.2.1.75 {ECO:0000313|EMBL:CAZ95366.1};
GN Name=hemD {ECO:0000313|EMBL:CAZ95366.1};
GN OrderedLocusNames=zobellia_1310 {ECO:0000313|EMBL:CAZ95366.1};
OS Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 /
OS NCIMB 13871 / Dsij).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Zobellia.
OX NCBI_TaxID=63186 {ECO:0000313|EMBL:CAZ95366.1, ECO:0000313|Proteomes:UP000008898};
RN [1] {ECO:0000313|Proteomes:UP000008898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC {ECO:0000313|Proteomes:UP000008898};
RG Genoscope - CEA;
RT "Complete genome sequence of Zobellia galactanivorans Dsij.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAZ95366.1, ECO:0000313|Proteomes:UP000008898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC {ECO:0000313|Proteomes:UP000008898};
RX PubMed=22513138; DOI=10.1111/j.1462-2920.2012.02751.x;
RA Thomas F., Barbeyron T., Tonon T., Genicot S., Czjzek M., Michel G.;
RT "Characterization of the first alginolytic operons in a marine bacterium:
RT from their emergence in marine Flavobacteriia to their independent
RT transfers to marine Proteobacteria and human gut Bacteroides.";
RL Environ. Microbiol. 14:2379-2394(2012).
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DR EMBL; FP476056; CAZ95366.1; -; Genomic_DNA.
DR RefSeq; WP_013992675.1; NZ_JAUOSS010000004.1.
DR AlphaFoldDB; G0L3D2; -.
DR STRING; 63186.ZOBELLIA_1310; -.
DR KEGG; zga:ZOBELLIA_1310; -.
DR PATRIC; fig|63186.3.peg.1295; -.
DR HOGENOM; CLU_076006_0_0_10; -.
DR OrthoDB; 1149788at2; -.
DR Proteomes; UP000008898; Chromosome.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR039793; UROS/Hem4.
DR PANTHER; PTHR12390; UROPORPHYRINOGEN III SYNTHASE; 1.
DR PANTHER; PTHR12390:SF0; UROPORPHYRINOGEN-III SYNTHASE; 1.
DR Pfam; PF02602; HEM4; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CAZ95366.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008898}.
FT DOMAIN 20..235
FT /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT synthase"
FT /evidence="ECO:0000259|Pfam:PF02602"
SQ SEQUENCE 248 AA; 28704 MW; 9CCEB85785AD4344 CRC64;
MKVKTILVSQ PEPKMENSPY SKLIDKEKVK VDFRPFIHVE GVDAKDVRQQ KIDLKNYTAI
ILTSRNAVDH FFRIAEEMRF KVPDSMKYFC QSEAVAYYLQ KYVVYRKRKI YVGKRNFADL
VPLFKKYKGE KFLLPSSDAL KPIIPEILDG LDIEWKRGIF YKTVISDLSD LRDVYYDILV
FFSPSGIESL LQNFPDFEQN DTRIAVFGNS TIDAATQAGL RIDIKAPTPE TPSMTMALQK
YITTVNKK
//
