ID G0L4I5_ZOBGA Unreviewed; 622 AA.
AC G0L4I5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:CAZ95728.1};
GN OrderedLocusNames=zobellia_1674 {ECO:0000313|EMBL:CAZ95728.1};
OS Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 /
OS NCIMB 13871 / Dsij).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Zobellia.
OX NCBI_TaxID=63186 {ECO:0000313|EMBL:CAZ95728.1, ECO:0000313|Proteomes:UP000008898};
RN [1] {ECO:0000313|Proteomes:UP000008898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC {ECO:0000313|Proteomes:UP000008898};
RG Genoscope - CEA;
RT "Complete genome sequence of Zobellia galactanivorans Dsij.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAZ95728.1, ECO:0000313|Proteomes:UP000008898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij
RC {ECO:0000313|Proteomes:UP000008898};
RX PubMed=22513138; DOI=10.1111/j.1462-2920.2012.02751.x;
RA Thomas F., Barbeyron T., Tonon T., Genicot S., Czjzek M., Michel G.;
RT "Characterization of the first alginolytic operons in a marine bacterium:
RT from their emergence in marine Flavobacteriia to their independent
RT transfers to marine Proteobacteria and human gut Bacteroides.";
RL Environ. Microbiol. 14:2379-2394(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP476056; CAZ95728.1; -; Genomic_DNA.
DR RefSeq; WP_013993036.1; NZ_JAUOSS010000006.1.
DR AlphaFoldDB; G0L4I5; -.
DR STRING; 63186.ZOBELLIA_1674; -.
DR KEGG; zga:ZOBELLIA_1674; -.
DR PATRIC; fig|63186.3.peg.1654; -.
DR HOGENOM; CLU_005912_10_1_10; -.
DR OrthoDB; 570124at2; -.
DR Proteomes; UP000008898; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008898};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..399
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 412..492
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02254"
SQ SEQUENCE 622 AA; 68744 MW; 853A6AD02F926C60 CRC64;
MVELAGIIIL GIIAQWVAWR FKLPAILPLI LIGLLVGPIS TLFTEDGTKL IRPIWNEKEG
LFLGESLYHF VSLAIGVILF EGGLTLKRSE VTRVGPVITK LITVGSAVTF FLAGTAAHFI
FELSWQISFL FSALIIVTGP TVITPILRNI PLKKDLSAIL KWEGILIDPI GALVAVLVFE
FISIGEGQGY TQTGLLEFVK VLLLGFTFGF TFAHALTLAI KRNYVPHYLL NVVSLSVVLS
VFVISELFAH ESGLLAVVVM GMVMGNTQLP NIKELLYFKE SISILLISML FILLSASMNL
PELELLYNYK TLILFAIVVF VVRPLGVFLS TAGSKLNFRE KLFISWVGPR GIVAAGIASL
FGSKLILRGE PGADYITPLV FMIVLGTVLL NASTARFMAK LLGVFLEKSE GIVIIGASKV
SRLIADYLHK NNRHVVLVDN NQTNIEKAQK LGIEAITANI YSDNLTDNIE LNDVGYLMAL
TGNSDINKYA VEKFGSQFGE NGSFRLIDSD EMNDPENNPK EGLFSHTDDF IKLTETARMF
PIIHEIEIKD KEHYEGLIEI TKADDHVVPI FLKTPDGDLK IIPSFSTDFE DISGGYRLVY
LGKILEVDET EDEVETKHQD EE
//
