ID G0M6Z4_CAEBE Unreviewed; 291 AA.
AC G0M6Z4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=CBN-HST-3.2 protein {ECO:0000313|EMBL:EGT30298.1};
GN Name=Cbn-hst-3.2 {ECO:0000313|EMBL:EGT30298.1};
GN ORFNames=CAEBREN_14983 {ECO:0000313|EMBL:EGT30298.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL379786; EGT30298.1; -; Genomic_DNA.
DR AlphaFoldDB; G0M6Z4; -.
DR STRING; 135651.G0M6Z4; -.
DR EnsemblMetazoa; CBN14983.1; CBN14983.1; WBGene00153708.
DR eggNOG; KOG3704; Eukaryota.
DR HOGENOM; CLU_017703_0_0_1; -.
DR InParanoid; G0M6Z4; -.
DR OMA; YFHSKMA; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:EnsemblMetazoa.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR037359; NST/OST.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10605:SF73; HEPARAN SULFATE 3-O SULFOTRANSFERASE-B, ISOFORM A; 1.
DR PANTHER; PTHR10605; HEPARAN SULFATE SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR637359-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..291
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003402777"
FT DOMAIN 29..275
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT ACT_SITE 38
FT /note="For sulfotransferase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-1"
FT BINDING 38..42
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 119
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 127
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT BINDING 255..259
FT /ligand="3'-phosphoadenylyl sulfate"
FT /ligand_id="ChEBI:CHEBI:58339"
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-2"
FT DISULFID 240..250
FT /evidence="ECO:0000256|PIRSR:PIRSR637359-3"
SQ SEQUENCE 291 AA; 33487 MW; 40FF7853BA458532 CRC64;
MKFRLLLILL LINAISSRFI PNTTKKRFPD AIIVGVKKSG TRALLEFLRI NPLIKAPGPE
VHFFDKNFNK GLEWYREQMP ETRIGEVTIE KSPAYFHSKM APERIKLLNP NTKIIIVVRD
PVTRAISDYT QSSSKRKRLG LMPSFETMAV GDCANWLRTN CTTKTRGVNA GWGAIRIGVY
HKHMKRWLDH FPIENIHIVD GEKLITDPAN EISATEKFLG LTPVAKPENF GVDPIKKFPC
IKNDDGKLHC LGKTKGRHHP DVEPNVLRVL KEFYGPENKK FYQMINHWFD W
//
