ID G0MIW7_CAEBE Unreviewed; 731 AA.
AC G0MIW7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=CBN-SPR-5 protein {ECO:0000313|EMBL:EGT31245.1};
GN Name=Cbn-spr-5 {ECO:0000313|EMBL:EGT31245.1};
GN ORFNames=CAEBREN_15713 {ECO:0000313|EMBL:EGT31245.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR038051-1};
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DR EMBL; GL379796; EGT31245.1; -; Genomic_DNA.
DR AlphaFoldDB; G0MIW7; -.
DR STRING; 135651.G0MIW7; -.
DR EnsemblMetazoa; CBN15713.1; CBN15713.1; WBGene00154438.
DR eggNOG; KOG0029; Eukaryota.
DR HOGENOM; CLU_004498_5_1_1; -.
DR InParanoid; G0MIW7; -.
DR OMA; SSRGEMF; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblMetazoa.
DR GO; GO:0140682; F:FAD-dependent H3K4me/H3K4me3 demethylase activity; IEA:EnsemblMetazoa.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0040029; P:epigenetic regulation of gene expression; IEA:EnsemblMetazoa.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.90.660.10; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR017366; Hist_Lys-spec_deMease.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR007526; SWIRM.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR PANTHER; PTHR10742:SF351; LYSINE-SPECIFIC HISTONE DEMETHYLASE 1-RELATED; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR Pfam; PF04433; SWIRM; 1.
DR PIRSF; PIRSF038051; Histone_Lys-demethylase; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50934; SWIRM; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR038051-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR038051-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT DOMAIN 27..125
FT /note="SWIRM"
FT /evidence="ECO:0000259|PROSITE:PS50934"
FT REGION 700..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 165
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR038051-1"
FT BINDING 171
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR038051-1"
FT BINDING 648
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR038051-1"
SQ SEQUENCE 731 AA; 82022 MW; 3D00B68EC348E8E2 CRC64;
MSSESGSGYL DEELRGEELG PMDENALSAA ATRSCLPYDR PTEHELAFFP ELWEHKTAVE
VYLLIRNTTL ATWHCNPLRE CTVSDVYGNV YPPFNSDLEL IQNIVNYLTR HAFINFGRYV
RCTKISRFLV RDERKVIVIG AGAAGIAAAT QLTSFGFDVT IVEGRNRIGG RAHGFRTKHG
QLVETGADTL RNIENTPIYT LLQQANLDEH GAFDHSFCYV DGKILPEEKA NLVIGHYHSA
KGALNWQAHQ NEHRDETGRF ISRQQAYENL INMCERTTLI KYYNHCKSLE SIARARQHHF
DHMKLLRNMA FLAENELGKM EKDGIDDPLR RRSLKRDIAT ALEKFEEIAN SFEACDGHWI
RLTEQPAAKQ YLLPGEDFST YNFMLGFEEY LIGADLEKVQ FTTDAVKNKE NGVAARLTEG
VQELLLRIVQ RRDLDIRLKS RVTDIDYSGH DNVKVTILKS DGQVEELTAG FVVSTIPIGV
LKKTIVSDEK APRFNPPLPA KKVDAIRNIG NGLINKCILE FDRPFWSTNG RTQFITVQPN
LKTRGSMSLW SSVPGSKVLT TYIVGQEAEN TIPDDVIVQN AMLNLQKVFG SQCPRTPVSA
HITRWQNDDL AGGSGAFMSL RTELHHFDDV RAALKTADGR KRVYFAGEHT CQEYTSTIQG
AWISGARAAT DIANDHNGIG FVDLTGNRKE AEEGEEMIEM DYDGPMPDDL TAFPELQGLR
DPNQPGTSSS A
//
