ID   G0MZJ2_CAEBE            Unreviewed;       337 AA.
AC   G0MZJ2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Selenocysteine lyase {ECO:0000256|ARBA:ARBA00040554};
DE            EC=4.4.1.16 {ECO:0000256|ARBA:ARBA00039054};
GN   ORFNames=CAEBREN_15676 {ECO:0000313|EMBL:EGT48316.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine
CC       and elemental selenium. {ECO:0000256|ARBA:ARBA00037407}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   EMBL; GL379822; EGT48316.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MZJ2; -.
DR   STRING; 135651.G0MZJ2; -.
DR   EnsemblMetazoa; CBN15676.1; CBN15676.1; WBGene00154401.
DR   eggNOG; KOG1549; Eukaryota.
DR   HOGENOM; CLU_003433_0_0_1; -.
DR   InParanoid; G0MZJ2; -.
DR   OMA; MINCETS; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.260.50; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR016454; Cysteine_dSase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR11601:SF62; SELENOCYSTEINE LYASE; 1.
DR   Pfam; PF00266; Aminotran_5; 1.
DR   PIRSF; PIRSF005572; NifS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT   DOMAIN          2..318
FT                   /note="Aminotransferase class V"
FT                   /evidence="ECO:0000259|Pfam:PF00266"
SQ   SEQUENCE   337 AA;  36534 MW;  C0AFA6C3D7821898 CRC64;
     MMFNVENDGV VFTSGDIESN NWVIEGSIRI ARKMNKTGTP HVVTTNIEDP SILEPLKKKE
     KAGEITVTYV AVNPSTGFVT AESILNALTP ATCLVTVMLA NSETGVLQPV SDIFHSIRET
     FKEKSPFLHS DVAQAAGKIL VDVKLLGADA VTVVGHKFHG PRNGALIFSP EGIRVLPMVL
     GENEESGWKH GAENTANIVG FGEAARMYGE NMNIETLLLQ NRDHFEELLV KNLRNSHVIN
     FMGSPRLPNT SSVAFIDYPS HSCDLLKKCK TFTASTGADC HKNEGSPVLK ACGVPFETAS
     KTVCFSFGRL TQLSEIETVV EELVQLCSPA EGSDNNI
//