ID   G0MZV2_CAEBE            Unreviewed;      1201 AA.
AC   G0MZV2;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   RecName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CAEBREN_32403 {ECO:0000313|EMBL:EGT48635.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL379823; EGT48635.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0MZV2; -.
DR   STRING; 135651.G0MZV2; -.
DR   EnsemblMetazoa; CBN32403.1; CBN32403.1; WBGene00194368.
DR   eggNOG; ENOG502RT8T; Eukaryota.
DR   HOGENOM; CLU_002807_0_0_1; -.
DR   InParanoid; G0MZV2; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd00047; PTPc; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR003125; WSN.
DR   PANTHER; PTHR32525; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR   PANTHER; PTHR32525:SF1; PROTEIN-TYROSINE-PHOSPHATASE-RELATED; 1.
DR   Pfam; PF02206; WSN; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SMART; SM00453; WSN; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        810..836
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          897..1139
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          1060..1130
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1201 AA;  135235 MW;  997E4339AD8B0450 CRC64;
     MALQYSEIQS QPQSGQQGIE GAIGPVKRNA PTDQLELFVK HSSIISRIAN GIALQTGLME
     GSIPIDGAVG ELLNFGSVSV SDVANFKGDN VSDLIGRLRI LPKDIDSSAK SLEDVALAWN
     QLRIDSESAK DAINPPRKED YFTALDTLSN SFDYKLLTTA YGEMEALFNR LNEIANKVAS
     GEPDASRLDS IYQLTFSNLP GNIQNFLDSL KNLPDLSKTI NQNDILVKSN EVFKPIQEAI
     RLFKNRGLIV KSTPGSLSIM ETNFRKAFEL ASAAASSLPQ TILLKSLTDS RVNSQAIQRK
     FTSAFSNGKH EIDELFADMH NKWIETVSRG NITQVMLTQS FSPLSFFKSK LTEIDKVFGS
     TLDKSSSESL VKMEEIQRKL SKFKEESVNS ASVIEQLENC KLQGPPLFDP SESVIIIENA
     KNLGEWLTRF NKKVLTLDLE KLKNETEKFK ESIGFTDWSD QKGSASQVPQ ALNNLRGNDI
     LSKFKTMIDG IKTGISVNVT KLQEDITSIK NGQGTVNSFN GLKEELELHE CLQQLKDQSE
     LLAHAIDTTR NLKKLDASNS KGQNTFNIDD FENIVNVVTG VSEKIEDIKS IPERMIKEAT
     SLTNETNRLP RNISEIVGSA VTSLRSAHEL KKLATASIPQ LKQIDNTIKN ELKAVTDPTK
     KKSIEDSWGD HDQDIATLED AIKQIEGVEG DMNLTDIKFI NQYGKPFLQL KQLKDMNIDT
     KSKIQALEML IPTSNSKGEL EKSKATLSTI DSLDLQFSNH HTQFEEASMA FQNFYKFFVD
     ITTSQKKKQS NLSSGNNGAD KDKKNQDPNY ALIGGVAGGG SVFIGGVIAA ALFVYFKYWK
     HRVNKNAIKK WIRKQMFPDS FRKNEKGKEY NEKYADAYRC HEALLKAMEI YVGRMQRSFE
     YLPENKHRDL HGVNPETALH HLMKDGVKMP INANWVIAPD GKKFIATSSP IIKSKKKEDT
     REDTREDFWH MVMLENVEYI VMLCLENEGN FRYYPAEINK SETFGRYTVE WVMDGTLGDF
     TQIKYKKLKI TTKGGKSSTV THFNYIGWPD GQPPEEGDLK NVYELLKYVE QTKAPVVVHC
     LAGIGRTMTF IGVYTTAEEV KVNPKLLWGE ALAKLREARW YAIQTIRQSY WLQVAVCDKL
     NRDLKLGMDE EIKSMHETFI HVAYDFDLPE EAKAAKAIKK KEMKKDPKRD KMLDFGRNIA
     Y
//