ID G0N5C0_CAEBE Unreviewed; 483 AA.
AC G0N5C0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAEBREN_06125 {ECO:0000313|EMBL:EGT53175.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL379840; EGT53175.1; -; Genomic_DNA.
DR AlphaFoldDB; G0N5C0; -.
DR STRING; 135651.G0N5C0; -.
DR EnsemblMetazoa; CBN06125.1; CBN06125.1; WBGene00144850.
DR eggNOG; KOG0789; Eukaryota.
DR HOGENOM; CLU_610079_0_0_1; -.
DR InParanoid; G0N5C0; -.
DR OMA; CSEASYI; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR23219:SF16; PROTEIN CBG07970; 1.
DR PANTHER; PTHR23219; TYROSINE-PROTEIN PHOSPHATASE C15H7.3-RELATED; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 433..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 158..450
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 361..441
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 55233 MW; 840F9C1C2C454B34 CRC64;
MTVSSKQSKG KQRNAKTPKP EDTMDEDEQE PKPPVSREPM SKEPMSKETS KEKLGITAAL
KETKKLIQGT GNKFKLKSKE KEKDRTTRER KAPSPSTPSG EKTEREINPN SNPNAKMVAA
IKGFCRYLLN MKESSLSTYF DERLAKYTPT NCTFSEWERN MAKNRSKEYK VSDASRVRLD
IAGKPAYINA SHIKFDPTCS EFILTQYPMK DTIHDFWRMV SQKKVNRIIT IFEPYVDEAI
EEFNKVPSLI SPAPVSVLDS INGPVLNLTE KSQTREQIMT VSIRCDTNQA KSSFFPLFTD
HYMNLDNWLI NTRKVEIDER NKNWMSLYTV EIVAEECSEA SYIRVFNCTT WPWKKVPNEE
KKLLALVRAP FKDESPLVAK QDKSEPIVVM CDLGLDRSAT VVLTTVIIEL VLAGKTPDCD
ALFKKMRDQR PNVFTMSIFY TYAIRAALFY LKMKHKTMGD PGGEEVNNMI TEALNKVPFV
SKK
//
