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Database: UniProt
Entry: G0N7N7_CAEBE
LinkDB: G0N7N7_CAEBE
Original site: G0N7N7_CAEBE 
ID   G0N7N7_CAEBE            Unreviewed;       940 AA.
AC   G0N7N7;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   05-JUN-2019, entry version 44.
DE   RecName: Full=Diacylglycerol kinase {ECO:0000256|RuleBase:RU361128};
DE            Short=DAG kinase {ECO:0000256|RuleBase:RU361128};
DE            EC=2.7.1.107 {ECO:0000256|RuleBase:RU361128};
GN   Name=Cbn-dgk-1 {ECO:0000313|EMBL:EGT54820.1};
GN   ORFNames=CAEBREN_23338 {ECO:0000313|EMBL:EGT54820.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-
CC         3-phosphate + ADP + H(+); Xref=Rhea:RHEA:10272,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:58608, ChEBI:CHEBI:456216; EC=2.7.1.107;
CC         Evidence={ECO:0000256|RuleBase:RU361128};
CC   -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase
CC       family. {ECO:0000256|RuleBase:RU361128}.
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DR   EMBL; GL379848; EGT54820.1; -; Genomic_DNA.
DR   STRING; 135651.CBN23338; -.
DR   EnsemblMetazoa; CBN23338; CBN23338; WBGene00162063.
DR   eggNOG; KOG1169; Eukaryota.
DR   eggNOG; ENOG410XQVB; LUCA.
DR   InParanoid; G0N7N7; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0030424; C:axon; IEA:EnsemblMetazoa.
DR   GO; GO:0044297; C:cell body; IEA:EnsemblMetazoa.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblMetazoa.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0017048; F:Rho GTPase binding; IEA:EnsemblMetazoa.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046834; P:lipid phosphorylation; IEA:EnsemblMetazoa.
DR   GO; GO:0040013; P:negative regulation of locomotion; IEA:EnsemblMetazoa.
DR   GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:2000292; P:regulation of defecation; IEA:EnsemblMetazoa.
DR   GO; GO:0046662; P:regulation of oviposition; IEA:EnsemblMetazoa.
DR   GO; GO:0032094; P:response to food; IEA:EnsemblMetazoa.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IEA:EnsemblMetazoa.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:EnsemblMetazoa.
DR   CDD; cd00029; C1; 2.
DR   Gene3D; 3.40.50.10330; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR020454; DAG/PE-bd.
DR   InterPro; IPR037607; DGK.
DR   InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR001965; Znf_PHD.
DR   PANTHER; PTHR11255; PTHR11255; 1.
DR   Pfam; PF00130; C1_1; 2.
DR   Pfam; PF00609; DAGK_acc; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   Pfam; PF00788; RA; 2.
DR   PRINTS; PR00008; DAGPEDOMAIN.
DR   SMART; SM00109; C1; 3.
DR   SMART; SM00045; DAGKa; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00314; RA; 2.
DR   SUPFAM; SSF111331; SSF111331; 1.
DR   SUPFAM; SSF54236; SSF54236; 2.
DR   PROSITE; PS50146; DAGK; 1.
DR   PROSITE; PS50200; RA; 2.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 2.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 3.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU361128};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008068};
KW   Kinase {ECO:0000256|RuleBase:RU361128};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00733152};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU361128};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transferase {ECO:0000256|RuleBase:RU361128};
KW   Zinc {ECO:0000256|SAAS:SAAS00732909};
KW   Zinc-finger {ECO:0000256|SAAS:SAAS00732991}.
FT   DOMAIN       20     70       Phorbol-ester/DAG-type.
FT                                {ECO:0000259|PROSITE:PS50081}.
FT   DOMAIN       83    131       Phorbol-ester/DAG-type.
FT                                {ECO:0000259|PROSITE:PS50081}.
FT   DOMAIN      149    200       Phorbol-ester/DAG-type.
FT                                {ECO:0000259|PROSITE:PS50081}.
FT   DOMAIN      264    353       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      355    454       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      534    672       DAGKc. {ECO:0000259|PROSITE:PS50146}.
FT   REGION      882    940       Disordered. {ECO:0000256|MobiDB-lite:
FT                                G0N7N7}.
FT   COMPBIAS    889    908       Polar. {ECO:0000256|MobiDB-lite:G0N7N7}.
SQ   SEQUENCE   940 AA;  105432 MW;  AA7CC7935E8A5101 CRC64;
     MAAEGHNVDA NLVDMRPNHG HYFVKKTFGK PTYCHHCCDK IWGMLTTGYS CEMCNFICHE
     KCLRTVVSYC SSVALQLIKN PVAHTWSAPC LIKRKYCCVC RKRTDEAMSV ECEVCEYYVH
     VDCSDLAVSD CKEAATYVAN MESANAVQYH HMREGNLPKE SKCVVCRKTC FSTECLAGMR
     CEWCGQTAHA VCYRQMDKEC DFGVLRKIVL PPMCLTIPRT ELPMEQLLNI SSHDQPQSRK
     VSSPSKIQAD DVSTTAEEIK ERDDFEVIRV FDGNNSYRLQ ISRNIIVAKH VSVQQVRDAA
     LRRFHINDTP ERYYITQVVG EVEEEILEDP VPLRNVKRPE GKRAQIFIRY YDDPDKDEVK
     VYGGWLRKVP VTFCAISVSK DTIVQDLVTD ALYHFGLDGA LWNRYNLIEV SLDRGVAERT
     CNPQENVLQL VRNLRKDSLR RYHVVRFYVQ EKEDPHDHAV FVGNLPVSLA QRQYERILLK
     LLGAKEKPFT AIGPIYFEYG SLIITFNTPK AATAAEKKLI VLCLPNVQPQ MIPKDVEPLL
     VLVNVKSGGC QGTELIQSFR KLLNPFQVFD VLNGGPLVGL YVFRNIPKYK ILACGGDGTI
     GWVLQCLDIA KQDAACFSPP CGIVPLGTGN DLARVLRWGG GYTGEENPMD ILKDVIEADT
     VKLDRWAVVF HEEERNQPTS SGTQTEMSEQ TMNNPEDQTS MIIMNNYFGI GIDADVCLKF
     HNKRDANPEK FQSRLFNKTQ YAKIGLQKMF FERTCKDLFK RIELEVDGRT IELPNIEGIV
     VLNLLSWGSG ANPWGTSKEE GNFSKPTHYD GLLEVVGISD VSRLGLIQSK LAAGIRIAQG
     GSIRITTHEE WPVQVDGEPH IQPPGTITIL KSALKAQMLK KAKKSRRGGN ASSLLNQAQD
     TTDPLSGPLG VPSTLGDPQH GKTTPDNTAA DSDEEGDAFL
//
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