ID G0NCI6_CAEBE Unreviewed; 628 AA.
AC G0NCI6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=phosphoenolpyruvate carboxykinase (GTP) {ECO:0000256|ARBA:ARBA00012306};
DE EC=4.1.1.32 {ECO:0000256|ARBA:ARBA00012306};
GN ORFNames=CAEBREN_29244 {ECO:0000313|EMBL:EGT57476.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [GTP]
CC family. {ECO:0000256|ARBA:ARBA00005796}.
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DR EMBL; GL379862; EGT57476.1; -; Genomic_DNA.
DR AlphaFoldDB; G0NCI6; -.
DR STRING; 135651.G0NCI6; -.
DR EnsemblMetazoa; CBN29244.1; CBN29244.1; WBGene00191209.
DR eggNOG; KOG3749; Eukaryota.
DR HOGENOM; CLU_460961_0_0_1; -.
DR InParanoid; G0NCI6; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:InterPro.
DR Gene3D; 3.90.228.20; -; 1.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008209; PEP_carboxykinase_GTP.
DR InterPro; IPR035077; PEP_carboxykinase_GTP_C.
DR InterPro; IPR035078; PEP_carboxykinase_GTP_N.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR PANTHER; PTHR11561; PHOSPHOENOLPYRUVATE CARBOXYKINASE; 1.
DR PANTHER; PTHR11561:SF2; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); 1.
DR Pfam; PF00821; PEPCK_GTP; 1.
DR Pfam; PF17297; PEPCK_N; 1.
DR PIRSF; PIRSF001348; PEP_carboxykinase_GTP; 2.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
PE 3: Inferred from homology;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT DOMAIN 61..300
FT /note="Phosphoenolpyruvate carboxykinase GTP-utilising N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF17297"
FT DOMAIN 405..623
FT /note="Phosphoenolpyruvate carboxykinase C-terminal P-loop"
FT /evidence="ECO:0000259|Pfam:PF00821"
SQ SEQUENCE 628 AA; 70119 MW; FC40D74ABE7A9AB6 CRC64;
MSKETDCPTC KYPSTQTRER VNEVCQFIVP RQSNTMVVPG YGQIPVVKGD LSCLSPEVSI
FLNECVQLMT PSTIRICNGS VFEAQELRDS IGNEFGSEEQ KVLDRLHFKM NDIGFDDIHV
ITKDRMDADP GTFSSTTTSS TNIHVSKSTS TDNMENVRLS SHYMTGKHFD FAKEKRFDGC
MSGRTMYVVP FSMGWIGSRH SIVGVQITDD PVLVLNLRCS FRVLPSVWDC IASSTNFIRS
VHSIGMPRPI IRRIVFPSPP EPPVGSFIVL KHDEQQVWAH GYPFGRTPRF GKTFSIHAAS
WIGAKRGWLA EQAAILAITN TKNETINVCY SSMTPVESLQ LLAGLANGWK IDVICEKSVW
IHWHNGKMHA FSPENDEMEE MGTQKNLSNL LSGSIQDYQI QGFNPQKTKW ERDVGVPISA
YIFANQRHDQ YPLILEANTW EEGVCLAAGI RVAMPKKSGS LEGTSATDPA QQQLVECPML
RPDSINFSFA KYVNHWLEMG IGVKTPSAES SESYDSPVPP QIFFTNLYQE ADGKVIWPGG
VDNAKVFEYI YGRCTNPSDT SNTVSSGVGK VPKNLELSAL VNLPPLLQIN IRFWLTELNK
LRSFFNAQME CCLPPQLDKV LTDLAGNL
//
