ID G0NKK8_CAEBE Unreviewed; 724 AA.
AC G0NKK8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=CBN-GLR-3 protein {ECO:0000313|EMBL:EGT32954.1};
GN Name=Cbn-glr-3 {ECO:0000313|EMBL:EGT32954.1};
GN ORFNames=CAEBREN_02363 {ECO:0000313|EMBL:EGT32954.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; GL379900; EGT32954.1; -; Genomic_DNA.
DR AlphaFoldDB; G0NKK8; -.
DR STRING; 135651.G0NKK8; -.
DR EnsemblMetazoa; CBN02363.1; CBN02363.1; WBGene00141088.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007257_1_1_1; -.
DR InParanoid; G0NKK8; -.
DR OMA; FAEWSSR; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF588; GLUTAMATE RECEPTOR IONOTROPIC, KAINATE GLR-3; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..724
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003405895"
FT TRANSMEM 489..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 366..711
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 376..433
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 724 AA; 81940 MW; EFB51D4D97113821 CRC64;
MAPFPLFLLL LSSLFPRVIV YKIVCNCLAL GASAIILPEQ YEGHLAAAAI VQSIADTTNV
PCVSLHLSPP TRPSTHLHPH LNAKSLAVAA FIKREKWKDV VVVFEEADEL LEVTDMITAG
HFDPDSFSSQ LVRLKHGDDY GNELKHIKNK LDRYRIVINI PLPRALHFLE QAANMSMCGV
LYHYVVMDMV GLQTTNATKT TKIQDLVTVD IDSMRGIADC NITSFGVHDV NSEFVEDMRQ
EIVHKSSIRL PKKGIPYTTS IWIDTLRLLI RSMKSIHIWE EPRCGDTWKA GSDIKKKFFE
TPLNGISGDL YWAPSGERSN YTLHVYRRKL TFQKFAEWSS RTRRIASSEA VVIANSSEKL
TLEGKHLKIS VYLEAPFVMM TSNGSYEGYC IDLLHKIANI LKFTYTIQKV RDNAYGSKES
NGKWSGMVGE LQRGDADLAV ASLTISYGRS EVIDFTVPYM HLGISILFKK PRITDSDWFK
FMDPLSTQVW IMTFASYFVV SVAIWIIANP YEQFERDEDN GQYKPVDNQF SLRNSFWFTV
CSLMQQGSEL CPRAASTRLL TAIWWFFALI LISSYTANLA AVLTTRRMET PIENADDLAG
QTKIKYGTLG RGSTMSFFNE SKIETYERMW QLMSGTPGLF VQSSKEGIAR VKSSDYAYLM
ESSMLEYAVE RDCELMQIGG LIDQKGYGIG LPKGSPYREK PSPAQSQVIR HVNVIPTFKF
EFFK
//
