ID   G0NZ37_CAEBE            Unreviewed;      1021 AA.
AC   G0NZ37;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGT41078.1};
GN   ORFNames=CAEBREN_20602 {ECO:0000313|EMBL:EGT41078.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL379987; EGT41078.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0NZ37; -.
DR   STRING; 135651.G0NZ37; -.
DR   EnsemblMetazoa; CBN20602.1; CBN20602.1; WBGene00159327.
DR   eggNOG; KOG0891; Eukaryota.
DR   HOGENOM; CLU_001279_0_0_1; -.
DR   InParanoid; G0NZ37; -.
DR   OMA; MAFRIEC; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05170; PIKKc_SMG1; 1.
DR   Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003152; FATC_dom.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR   InterPro; IPR014009; PIK_FAT.
DR   InterPro; IPR039414; SMG1_PIKKc.
DR   PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR   PANTHER; PTHR11139:SF71; SERINE_THREONINE-PROTEIN KINASE SMG1; 1.
DR   Pfam; PF02260; FATC; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
DR   SMART; SM01343; FATC; 1.
DR   SMART; SM00146; PI3Kc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51189; FAT; 1.
DR   PROSITE; PS51190; FATC; 1.
DR   PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..282
FT                   /note="FAT"
FT                   /evidence="ECO:0000259|PROSITE:PS51189"
FT   DOMAIN          485..826
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50290"
FT   DOMAIN          989..1021
FT                   /note="FATC"
FT                   /evidence="ECO:0000259|PROSITE:PS51190"
SQ   SEQUENCE   1021 AA;  116835 MW;  0B90DDC7A8E58E5E CRC64;
     MLSEGYVNEI AKQDEHISRA SIQLGDLFET IPYVDNVLSP NLFPTRIWSE IQRRSDELSI
     GYYGFIGALY HLASETCPSL AKAHLKMAKW AYEMTQTKNC QEILPFTSYA FGQSQQEHDE
     LWNCLETTCL VNLEKQVRNL INDVARANML LSPGSHFLRA WEIISEHKRK FLSIAVSSYF
     QFIHSMSGDC DSLPYSRKEE TTLATLRILE LLVKHGDILI DVINDGLSTT NVHIWKEILR
     QLFARLSHPS DHIRKTLVDL ISRICTAAPH AVVFQVVSGA ASSTSTEIGE DLEEQQNDDR
     NRVRACCEQL QTKMTQSYPS LVRDVSLFVA ELERINLLNE EKWSVVLGTM EHEMEKRLTL
     IRTENNKTEM AMHLMPAMKD DIIAKKTILL TPKTKNEEEF VTTFAELLTN AHQESRQSRL
     ISPEKSWVPF KNLIANFVHR TIKKGMQLFE TEEISPYLAN LVNSCVPMPG QESVEFDRAV
     SIARVSKQVT ILPTKTRPKK LGFIGSDGKQ VAFLFKGRED LHLDERVMQF LRLCNVMLQP
     GKGKTRQIAE YQAHHYAVIP LGPRSGLIKW VEGATPIFHI YRKWQMKEKA LKQASKKNGE
     TVPDVERPSN MYHNMMRESF NAHKIDATVA ADRTKWPLFI YEEVFAGLCE KTPTDLISIE
     KSNDANTWWS VTKRYARSLA VMSMIGSVLG LGDRHLDNLL VDLKWGHVVH IDYNICFDKG
     KNLRIPETVP FRLSRNMRHA LGPSEMYGTF RESCVHVLST LRSGHQVLTM LLDAFVFDPL
     VDWTSHEHSS TSGVSLALQL AVYGSEWKSK ARERLTDTME LLQLRMNEMQ SLWKNNRDDL
     LLWMKQVTDC LMLEKSILEA NGIYAQQRVK AGTELREAVT RHQALAKELR PLIRAIGKER
     EEFAGYMKFY KRGFIDPLLK GHSALRHEVD IDTCVQNFNI VMQNIDIVFG SLVNLSSMPI
     ETITAPREVV KRVERRLNGW LDGSATTDRK MSPREEVDHL IAEATSTTNL SQMYEGWTAW
     V
//