ID   G0P5H3_CAEBE            Unreviewed;       830 AA.
AC   G0P5H3;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=FAD dependent oxidoreductase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CAEBREN_06461 {ECO:0000313|EMBL:EGT45455.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; GL380083; EGT45455.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0P5H3; -.
DR   STRING; 135651.G0P5H3; -.
DR   EnsemblMetazoa; CBN06461.1; CBN06461.1; WBGene00145186.
DR   eggNOG; KOG2844; Eukaryota.
DR   HOGENOM; CLU_007884_11_0_1; -.
DR   InParanoid; G0P5H3; -.
DR   OMA; QTEWDMW; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT   DOMAIN          31..392
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          395..444
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          451..714
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          752..824
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   830 AA;  92074 MW;  0D0CDDFE4C9ECC9F CRC64;
     MLHASRSLIR TSSDLHTSIR NSSSTKHVFA CVLGSGVAGS SVAYHLTKRN IKDVLLLERA
     SGVASPSGTS FHSPGLVSAS HPAHRYKPIL AHSIELYSKL QEETGVNIDF QPTGTIRLAT
     NETRLAEFRK YVNRDYYKEG DVCKTTLLTP DQVRELAPAV DHSKVLGALH TTNDGTISAR
     ALTQALVVGA KNGGAQVIDG AIPREIKYDK EKGHWIVALE DGTLVTTRNL INAGGIWAND
     IARLSGHALP VVVVEHQYAV LTPNKTPENT PAIIDHDSTF YVRKSGDDYL FGGFESLEKT
     VIREDWYKKG VPTEGSKSIK ADFSRLEDAY KRARELIPSL EGAKVDARAA VFSMTPDGYP
     LVGPYDKNYW MSTGFLDGVS SGGGIGKYLA DWIVDGEPPA ELFDTDASRY ERWGDRKFFT
     ERSRETYSMY YNWSYTDRLA GRPTDRISGI YGRLKKDGAS FSFRNGWEVA NSFNMGVQNE
     EFLPTLIREY EMVTNKCGVI DLSWKGKIEV KGKDAEKLMD YAIASQIPPL GKISSGLMLT
     RHGGILGPMM IFHHDRQRSA FILLTEPERE SRDLYWLRRA AAEKKLDVQV SIVSEYLASL
     ALVGPKSREV LSALTKSDVS DEGFPQKSTR MIRLGPVGVV CARSSTSTGQ LSYELFHNRA
     ETAKLYNAVM SAGREHGIVN FGQAALNMMR LEHGYKIWGR ELTLDTNPFE CGIGGLVDFN
     KKEFIGRESA LELSKKQFDR RLALITFDTE EGIVLDDKFV PSGNEVIRID GKEERVGQIT
     SGAYNVRLQK PIAFAWIDNA VGKDERLVVE IGDKRLFATS LETPTIPPIQ
//