ID G0P761_CAEBE Unreviewed; 736 AA.
AC G0P761;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGT46828.1};
GN ORFNames=CAEBREN_12416 {ECO:0000313|EMBL:EGT46828.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GL380108; EGT46828.1; -; Genomic_DNA.
DR AlphaFoldDB; G0P761; -.
DR STRING; 135651.G0P761; -.
DR EnsemblMetazoa; CBN12416.1; CBN12416.1; WBGene00151141.
DR eggNOG; KOG1216; Eukaryota.
DR eggNOG; KOG2579; Eukaryota.
DR HOGENOM; CLU_318131_0_0_1; -.
DR InParanoid; G0P761; -.
DR OMA; CATGCPL; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR PANTHER; PTHR46160:SF5; PROTEIN CBG11501; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00094; VWD; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
FT DOMAIN 4..186
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 434..471
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 470..725
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT DISULFID 461..470
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 736 AA; 83304 MW; CF4BB5ADEF6DE8DF CRC64;
MKVKKTCMSG DPHYVTYDGL HFDYQGTCPY VFTQPCTILP EPYGWFSVRA KNEFQNKNAN
VSIVSEVEVD LHNLTIHIDG RSKTALVNGV RVLTPWYYPD TKNWTVRITY TEPTFTIEND
QGIVVTFYYY YSLCVQVPDI PEFNGNSTLC GLGGNIDSNK FDDVVNKNGT VLDLKNTDRQ
PKNDNYLDFM KTEDTWITDN FLPLRPNQEN CLSGHLLNNI THCDIQSAAQ ACYPIQQAEN
GVGPFAACQG LGNDTLENFY YDCIYDTCRD PNYKCTEFTY FFRYCQQALP QEPMNKDWRS
EVNCPLACTP NAHPSICTSS CPSTCSEPFP EVCDKGCIDG CECDPGYVID NTVTGSMKCI
RIDQCGCTDT NGNPHQAGKP WLTQNCTIVH ECQNGSMWSY YKPCSDYGSC VINSVDMQCQ
CDKGFRGDGY NCTDINECVE TPGICNHGQC VNTPGSYHCD CEDFWVGDNC NAYKPRRHCA
DLYVYWDIRA NGVNYINPPF ALPNRTKFQA MDVFCDMTTN GGGYTLMSSD TKDLNSNKTF
QEYINGFGTL AAQSVWIGLE FIHQMTFYQP QTLRLNLHRC ASNGRPELDT YCTYPTFSVL
NSTTQYSVVI RESCTGTEAD GHYYQDGWAR WDLSQNGPKF STWDLEVETT RPTRLFENDA
ATFACTCSKN NLNTGWWYIE DQLCGAANLN GVRYSCPNIP VEDEKYLRWA EGTLGQASMW
LRPVGFPNYD KSMSSF
//
