ID G0PNZ5_CAEBE Unreviewed; 839 AA.
AC G0PNZ5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|SMART:SM00181};
DE Flags: Fragment;
GN ORFNames=CAEBREN_28836 {ECO:0000313|EMBL:EGT48048.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; GL382651; EGT48048.1; -; Genomic_DNA.
DR AlphaFoldDB; G0PNZ5; -.
DR STRING; 135651.G0PNZ5; -.
DR EnsemblMetazoa; CBN28836.1; CBN28836.1; WBGene00190801.
DR eggNOG; KOG1215; Eukaryota.
DR HOGENOM; CLU_339089_0_0_1; -.
DR InParanoid; G0PNZ5; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 4.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 7.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR22722:SF14; MEGALIN, ISOFORM A; 1.
DR Pfam; PF00057; Ldl_recept_a; 6.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00192; LDLa; 7.
DR SMART; SM00135; LY; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 7.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS01209; LDLRA_1; 5.
DR PROSITE; PS50068; LDLRA_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 19..55
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 257..294
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 298..333
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 701..739
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DISULFID 20..32
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 27..45
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 39..54
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 114..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 126..141
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 167..182
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 789..801
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 796..814
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 808..823
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGT48048.1"
SQ SEQUENCE 839 AA; 93975 MW; 01C5C376946E73CC CRC64;
GVADCANGSD EENCPRRKLC DATEFRCGNG LCIKQNFVCD GKMQCLDGLD EEHCEEEDCI
KGREFRCKNG NSACMDLIFR CDGVPDCEDE SDESEEFCKG NSSSTCAKMN QFMCADGKCL
RSFQLCDGFP DCLTGEDEKD CPASMCNSTT HFSCSSGNKC VSKQLECDGV DDCGDNSDEA
HCKTVRTNCF SDSNKQTIHF QASELRCLSD DSDGTTPSSS LFKCHGNKVK CISDKLLCDG
KKDCDEGDDE GLWCSIKCDP SDLGCSHTCR NTPFGPICSC PDDHYLAKDH ATCTKKSPCR
FGQCSQHCIP HGSTHFCYCE DGFKLSSDKF SCYSDDPQKP FLIYSNRHEI RMIQSKYPGS
SPMISNLVNA IALDFKYHQN GSVSIYWTDL SSDKIYSGLV EQRTISYQRT IVSYGVFNAE
GICRPIWITG KYSTGIDSYL GKLISSGVSE KRKKRKQTIG AVTADGERGR IYFADYDKFR
ISAVNFDGSG CVVIAEDVGV VPSMTYDEVN RELYFIRANP ASIWRIDVAD NNLETYPTEP
RIVLTLTIRD RPRHIAIHPC RSLLFFTNNA ITGSVIEQVY FSGFKRTQIV QEDLHDLRGL
TIDLDSEKLY FSDSKDFKLS RCDFDGTNRE LVVSNSDIPS IHPFELAVYE NEIIFTDWVR
RSVVAINKIT GTDNRTLNRA IEVPNSIVYF LNSCVSGTEN ACFNNDLKCE DYCRLMADGQ
PTCACNGERR LNSDNRTCTG ERNEKKCAEN EFKCLHSDRC IRYEDTCDQF NDCPMFDDED
AKYCSTRVCR PGYFTCGNGL CIPESKVCNR VNDCTNFADE ANCTCSAMNS DVLLEHVFP
//
