ID G0RAF3_HYPJQ Unreviewed; 1521 AA.
AC G0RAF3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Guanine nucleotide exchange factor for ADP ribosylation factors {ECO:0000313|EMBL:EGR52120.1};
GN ORFNames=TRIREDRAFT_55415 {ECO:0000313|EMBL:EGR52120.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR52120.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR52120.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
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DR EMBL; GL985057; EGR52120.1; -; Genomic_DNA.
DR RefSeq; XP_006962471.1; XM_006962409.1.
DR STRING; 431241.G0RAF3; -.
DR EnsemblFungi; EGR52120; EGR52120; TRIREDRAFT_55415.
DR GeneID; 18485845; -.
DR KEGG; tre:TRIREDRAFT_55415; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_55415; -.
DR eggNOG; KOG0928; Eukaryota.
DR HOGENOM; CLU_001204_3_1_1; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008984}.
FT DOMAIN 635..825
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1502..1521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1521 AA; 167414 MW; D997544AAC072BB5 CRC64;
MAPPSPVRSV RPASPSVHHE IPRMQYRSRP VSVAVDPVSL VISECIAITS AIQKHARSPH
FSVSAILGGN PNTIQFGSPK PRERGVGGGP FRDGDRDEAA SSRWSFQGQR AKGLQDSPMI
TGFSNLRHEI TGVQNIHSFD ALTLLAPFLF VIQEKGTAAP ITILALGALR KFLAYGFISP
ESPRFALAMQ SLSAAVTHCQ FDISDSAQGE VVLLMILNLM EDMMSGPGGY ILSDESVCDM
MGRGLAICSQ PRFSPVLRRT AEAVLVRMCQ IIFEDIKHIE VEAGDDSSVM DQLADQHMEN
VKMDTTAGSA VAEPIVPATT GDSPPAMGAP DSSEPEKAEE GRGDGEKADE GPVLDPDNED
NGESDTESLD LRPYSLPSVR ELFRVLVNFL DPNDRHHTDT MRVVALRIIH VALEVSGSFI
ARHPALATIA KDQLCCYLFQ LVRSDNMAIL QESLTVTGTL LATCRGILKL QQELYLSYLV
ACLHPKVPIP REAGIDPSLY AGIPETPKLV KPPPSQTNSG RATPVPVKDR QKLGLEGGAR
KPDARQAMVE ALGVLSRMPT FATELFVNYD CDEDRSDLCE DVIGLLARNA LPDSATWSTT
SVPPLCLDAL LRFIQFMAER LNDEPVYENC PDPEELREKR RKKRKIIIGT SKFNEKPKLG
LSYLEANNII TNINDPVSVA KFLKGTSRIS KAVLGDFLSK KGNEAILAAF MDLFDFSGKR
IDQALRLLLE SFRLPGEAPL IAAVVESFSE KYCDCNTLSE VANKDAVFIL TYAIIILNTD
QHNPNVKSMK RMTLNDFSRN LRGQNDGKDF SPDYLRDIYE TIKSNEIILP DEHDNQHAFD
YAWRELLVKS ETAGNLFLCD TNIYDGDMFA ATWKPVVSAL SYVFMSATDD AVFARIVTGF
DECARIATKY GNVEALDQIV YCLSHITTLA TRVPFNTSLN TEVQVGDGSV MVSELAVKLG
RDFRAQLAVL VLFRVVTGSE ALIQDGWKHI IQIWIHLFLN SLAPPLSSTD LPTLPIPAIP
LQTPSQVIDR AARSNDVGFF SAFTSYISSY AADDPPEPSD EELESTLCTV DCINSCHIDK
VLNNISKLPP ARIDILVQAL LDQLPESDPS AVIGVKQDNV AVVPPNGPNP ATGLPSYDPS
TPFILELCTI LTIRDGGCDP TTTKQDHDFV NVPIFLHTIS SLPQDLLLKT ADIILSGLSI
CTRDPGPLRS EMMTSPDFWV ILRVVAGDAN AAAQIFDILE RSTTGTPPAI MADNYEAAIS
LLNHFASAAD PLAARDPKSP EATRKKVDPQ VTARGCQAVN ALYGMTARIP QLMQQSHLES
SEAWSAYWLP ILQALTTQCT NSCRDVRQLA FSALQRSLLS PELTCSDPKE WTAIFSKVLF
PLIFRLLKPE VYSSDREGMS EMRVQVASLL CKVFLQYMVL LSEWDGMLDL WIKIIEIMDR
LMNSGQGDSL AEAVRENLKN VVLFMATSGY LVSPAKDPSR KKLWDETWER VNRFLPDLRN
EILGEEVPEQ SGEAKEDEEK Q
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