ID G0RH76_HYPJQ Unreviewed; 446 AA.
AC G0RH76;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Adaptor protein complex AP-1 medium subunit {ECO:0000313|EMBL:EGR49584.1};
GN ORFNames=TRIREDRAFT_60243 {ECO:0000313|EMBL:EGR49584.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR49584.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR49584.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
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DR EMBL; GL985062; EGR49584.1; -; Genomic_DNA.
DR RefSeq; XP_006964712.1; XM_006964650.1.
DR AlphaFoldDB; G0RH76; -.
DR STRING; 431241.G0RH76; -.
DR EnsemblFungi; EGR49584; EGR49584; TRIREDRAFT_60243.
DR GeneID; 18486595; -.
DR KEGG; tre:TRIREDRAFT_60243; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_60243; -.
DR eggNOG; KOG0937; Eukaryota.
DR HOGENOM; CLU_026996_0_0_1; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0030121; C:AP-1 adaptor complex; IEA:EnsemblFungi.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IEA:EnsemblFungi.
DR GO; GO:0099638; P:endosome to plasma membrane protein transport; IEA:EnsemblFungi.
DR GO; GO:0006895; P:Golgi to endosome transport; IEA:EnsemblFungi.
DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:EnsemblFungi.
DR GO; GO:0006896; P:Golgi to vacuole transport; IEA:EnsemblFungi.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:EnsemblFungi.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529:SF262; ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT; 1.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 2.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 167..441
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 446 AA; 50442 MW; 17CEB9EA8063A53F CRC64;
MASALFFLDL KGKTLLARNY RGDIPMSAVE KFPVLLSEAE EESSAVPPCF SHEGINYLYI
RHNNLYLLAL TKRNTNAAGI LLFLHKVVEV FTEYFKALEE ESIRDNFVVI YELLDEMMDF
GYPQTTESKI LQEYITQESH KLEIQARPPI AVTNAVSWRS EGIRYRKNEV FLDVVESLNL
LVSANGNVLR SEILGAIKMK CYLSGMPELR LGLNDKVMFE TTGRSTRGKA IEMEDVKFHQ
CVRLSRFEND RTISFIPPDG EFELMSYRLN TQVKPLIWVE CLVESHSGSR IEYMLKAKAQ
FKRRSTANNV EIIVPVPDDA DSPRFRTNIG SVHYAPEQSA IVWKIKQFGG NKEFLMRAEL
GLPSVRGDDE HGGGMTGGFG GSMGGIGGKG AKRPIQVKFE IPYFTTSGIQ VRYLKITEPK
LQYPSLPWVR YITQSGDIAV RLPDVV
//
