ID G0RIY0_HYPJQ Unreviewed; 439 AA.
AC G0RIY0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
DE Flags: Fragment;
GN ORFNames=TRIREDRAFT_26598 {ECO:0000313|EMBL:EGR48961.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR48961.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR48961.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC {ECO:0000256|ARBA:ARBA00010107}.
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DR EMBL; GL985063; EGR48961.1; -; Genomic_DNA.
DR RefSeq; XP_006964848.1; XM_006964786.1.
DR AlphaFoldDB; G0RIY0; -.
DR STRING; 431241.G0RIY0; -.
DR EnsemblFungi; EGR48961; EGR48961; TRIREDRAFT_26598.
DR GeneID; 18484352; -.
DR KEGG; tre:TRIREDRAFT_26598; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_26598; -.
DR eggNOG; KOG2747; Eukaryota.
DR HOGENOM; CLU_011815_0_1_1; -.
DR OrthoDB; 118560at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.60.60; N-acetyl transferase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002717; HAT_MYST-type.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR10615:SF180; HISTONE ACETYLTRANSFERASE SAS2; 1.
DR Pfam; PF01853; MOZ_SAS; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51726; MYST_HAT; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 26..371
FT /note="MYST-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51726"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 286
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR602717-51"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGR48961.1"
FT NON_TER 439
FT /evidence="ECO:0000313|EMBL:EGR48961.1"
SQ SEQUENCE 439 AA; 48656 MW; FD81198B2AC1152A CRC64;
PTPMVITPVL PPKPPTLPVS DRPPPRTDRN IDKVVLGNLC FRTWYPSYYG KEVLGATSSH
AKGGSKDGLL DAAGRGPSKK DKDGLPMLER LYVCPSCFKY AKELVAWWGH VKLCQQRAHI
PGNKIYVHPK GRRTVYVPQD GSRGPGQKKR RGEGNIRYVE EVVQDEGEWS LWEVDGEKDV
LFCQNLSLFA KLFLDNKSVF FDVTGFNYFL LVYTPPPAVA TSAGVAPPPV TPQITGFFSK
EKMSWDNNNL ACILIFPPWQ RKGLGALLMG ASYEISRREG IMGGPEKPIS DLGKKGYQRF
WAGEIARWLL SLDVAPADAE SGQETLVDVE DCSQATWISP EDCLGVLRDM GVAEDAGMQM
QASEEDKKKK PAATGEEDAA KQNIKRASAE AEEDEERPKP KPAAVKQVPR VRIDKEAVRR
YVAAHRLVLD RTCDPSGFV
//
