ID G0RM07_HYPJQ Unreviewed; 652 AA.
AC G0RM07;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Peroxisomal targeting signal receptor {ECO:0000256|ARBA:ARBA00014710};
DE AltName: Full=Peroxin-5 {ECO:0000256|ARBA:ARBA00032505};
GN ORFNames=TRIREDRAFT_22563 {ECO:0000313|EMBL:EGR47747.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR47747.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR47747.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SUBUNIT: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting
CC translocation through the PEX13-PEX14 docking complex.
CC {ECO:0000256|ARBA:ARBA00038659}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix
CC {ECO:0000256|ARBA:ARBA00004253}.
CC -!- SIMILARITY: Belongs to the peroxisomal targeting signal receptor
CC family. {ECO:0000256|ARBA:ARBA00005348}.
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DR EMBL; GL985067; EGR47747.1; -; Genomic_DNA.
DR RefSeq; XP_006966208.1; XM_006966146.1.
DR AlphaFoldDB; G0RM07; -.
DR STRING; 431241.G0RM07; -.
DR EnsemblFungi; EGR47747; EGR47747; TRIREDRAFT_22563.
DR GeneID; 18484150; -.
DR KEGG; tre:TRIREDRAFT_22563; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_22563; -.
DR eggNOG; KOG1125; Eukaryota.
DR HOGENOM; CLU_013516_3_0_1; -.
DR OrthoDB; 2020042at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR024111; PEX5/PEX5L.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10130:SF0; GH08708P; 1.
DR PANTHER; PTHR10130; PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
PE 3: Inferred from homology;
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT REPEAT 361..394
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 472..505
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 514..547
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 181..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 652 AA; 72267 MW; 67B9DE62B8844AD7 CRC64;
MSFMGGAECS TAGNPLSQFQ KHVQDDKTLQ RDRLVGRGPG GQLGGFRSSP ANAAQDEMVN
GFLNAGPGLQ QEFPTLQGAP GAQLGPAPIA NSMAPQWAQD FNAQGGMELM HQAPPRALFS
PEEFARFQQA NPAAAAAMAP EMRGDMSSAM PQQRPMMGMG MGMMGMPMGY GLANQSMMQP
MYQQQQQQQQ PVQQQQQDLK GKGKMVELDD SKWEEHFAQL ELQDKEEAKE AEKQATAAEP
ELNEMDNKLQ SETNEFGDFE SIWKGIQAET AAARSMVNEQ QYFDQFDTEW GQDLMPDFNG
VNDWGRFADP IVEKYMFEQE NIFRDQKNAF EEGVRVMKEG GNLSLAALAF EAAVQQNPEH
VEAWVYLGSA QAQNEKETAA IRALEQALKL DPNNLDAMMG LAVSYTNEGY DSTAYRTLER
WLSVKYPNIL DPTNLHPVAD MGFTDRQQLH DKVTNLFIKA AQLSPDGEHM DPDVQVGLGV
LFYGAEEYDK AVDCFQSALH SSELGTTNQQ EQLHLLWNRL GATLANSGRS EEAIAAYEQA
LSLAPNFVRA RYNLGVSCIN INCHQEAASH FLAALDMHKT IEKSGRSKAY EILGDGAAGQ
VDQALDRMSA QNRSSTLYDT LRRVFTQMGR KDLADKTVPG VDPDIFRPEF EF
//
