ID G0RSV1_HYPJQ Unreviewed; 592 AA.
AC G0RSV1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Gamma-glutamyltranspeptidase {ECO:0000313|EMBL:EGR45671.1};
GN ORFNames=TRIREDRAFT_5337 {ECO:0000313|EMBL:EGR45671.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR45671.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR45671.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
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DR EMBL; GL985077; EGR45671.1; -; Genomic_DNA.
DR RefSeq; XP_006968263.1; XM_006968201.1.
DR AlphaFoldDB; G0RSV1; -.
DR STRING; 431241.G0RSV1; -.
DR MEROPS; T03.025; -.
DR EnsemblFungi; EGR45671; EGR45671; TRIREDRAFT_5337.
DR GeneID; 18485528; -.
DR KEGG; tre:TRIREDRAFT_5337; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_5337; -.
DR eggNOG; KOG2410; Eukaryota.
DR HOGENOM; CLU_014813_3_1_1; -.
DR OrthoDB; 2910309at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0103068; F:leukotriene C4 gamma-glutamyl transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR Gene3D; 1.10.246.130; -; 1.
DR Gene3D; 3.60.20.40; -; 1.
DR InterPro; IPR043138; GGT_lsub_C.
DR InterPro; IPR000101; GGT_peptidase.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR NCBIfam; TIGR00066; g_glut_trans; 1.
DR PANTHER; PTHR43881; GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580); 1.
DR PANTHER; PTHR43881:SF1; GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580); 1.
DR Pfam; PF01019; G_glu_transpept; 1.
DR PRINTS; PR01210; GGTRANSPTASE.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008984}.
FT ACT_SITE 388
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ SEQUENCE 592 AA; 63891 MW; 837E2A2765807C47 CRC64;
MPFDAVGAVG EAPSDGADAL FDPSAPFFNR FNSRRSVVYS TKGIVAASQP LAAQAGLDIL
KAGGNAVDAA IATAAALGVT EPCSTGVGGD MFMIYWDDKK QKAFAINGSG RLPAGLTIEK
CRELGLTGNL LPPQDANSVT VPGQVAAWFD AKDAYGSGKV TMEQILKPAI ELCEDGFPVS
EVTARQWIEC EGLLKRVSPS GGELLLDGKA PRAGQVFKNP NLAKVLREIA SKGKAGFYEG
WVAEAITSEI QQLRGVMTMQ DLKDHTTTFV EPISKTYKEY KLLECPPNGQ GIVALEALGI
IDNLEKEGKI PSFKSLGHNS VQYVHTLVEA LRYAFADADA YVSDPEHSGS AWKGLLDDDY
LKERATKFTL DAVDTSLKNG FPSKSSDTVY FTTSDSEGNA CSFICSLASN FGGGIVPKGC
GFALQNRGTQ FQLREGHVNT LRPRKRPYHT IIPAMVTNND RLHLSLGVMG GFMQPQGHLQ
VMLNSCVFGF NPQDALDAPR VCIRPSRTLP EYATADDYSQ LTQKSMICLE EGFPEETVEG
LRRLGHEVQL VTGWDRAVFG RGQVIQAKRD TSGLQVWHGG SDQRGDGHAV VW
//
