ID G0RVQ8_HYPJQ Unreviewed; 476 AA.
AC G0RVQ8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Glycoside hydrolase family 30 {ECO:0000313|EMBL:EGR44753.1};
GN ORFNames=TRIREDRAFT_69736 {ECO:0000313|EMBL:EGR44753.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR44753.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR44753.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
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DR EMBL; GL985085; EGR44753.1; -; Genomic_DNA.
DR RefSeq; XP_006969347.1; XM_006969285.1.
DR AlphaFoldDB; G0RVQ8; -.
DR EnsemblFungi; EGR44753; EGR44753; TRIREDRAFT_69736.
DR GeneID; 18487873; -.
DR KEGG; tre:TRIREDRAFT_69736; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_69736; -.
DR eggNOG; KOG2566; Eukaryota.
DR HOGENOM; CLU_014379_3_1_1; -.
DR OrthoDB; 5487508at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR PRINTS; PR00843; GLHYDRLASE30.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361188};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..476
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003408561"
FT DOMAIN 64..401
FT /note="Glycosyl hydrolase family 30 TIM-barrel"
FT /evidence="ECO:0000259|Pfam:PF02055"
FT DOMAIN 405..470
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
SQ SEQUENCE 476 AA; 51578 MW; 289ADB03CEA4B5C0 CRC64;
MLFISVLTTI AAVGGVNAAS SFASTADGRN QFTPIQAPVL NAANPGIDNW KFTIKEKTGR
KQTVKGFGAA VTDATVAAFN KLNANLRSQL LNEIMTPAGL NFNLLRHTVA SSDLSADPAY
TYDDAGGKVD TGLNSFGLGD RGNAMISMLA NMRKLQSNLT ILGSPWSPPG WMKVKGQLIG
GGTANNKLNH AYEDAYAQYF VKYLKAYESG GAHIDAITLQ NEPLNNKDDM PTMLIQQDES
GALIRDKVGP ALRNAGLSTQ IWAWDHNQDV YSYPQTVMNM ASQYVQAAAW HCYAGNNPDN
WTPLTKFHNE FPGKDQYMTE CWTAVGTTDW VHSSSFNMFP LQNWANGVIA WTLGSFTGGG
PALSGGGNCH QCTGLVTVSP DGSSYKKEID YYMMGQFSRY IPKGAVVVDG TGSYLFPDNT
GMEAVGTINP DGTRTVVIQN RYNHDIWVQV GTESESQTWN ARVPGSSVTT WILPKA
//
