ID G0RWH0_HYPJQ Unreviewed; 723 AA.
AC G0RWH0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit {ECO:0000256|ARBA:ARBA00015765};
DE AltName: Full=ERF-3 {ECO:0000256|ARBA:ARBA00031881};
DE AltName: Full=ERF2 {ECO:0000256|ARBA:ARBA00030845};
DE AltName: Full=Polypeptide release factor 3 {ECO:0000256|ARBA:ARBA00029585};
DE AltName: Full=Translation release factor 3 {ECO:0000256|ARBA:ARBA00030210};
GN ORFNames=TRIREDRAFT_70305 {ECO:0000313|EMBL:EGR44499.1};
OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=431241 {ECO:0000313|Proteomes:UP000008984};
RN [1] {ECO:0000313|EMBL:EGR44499.1, ECO:0000313|Proteomes:UP000008984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QM6a {ECO:0000313|EMBL:EGR44499.1,
RC ECO:0000313|Proteomes:UP000008984};
RX PubMed=18454138; DOI=10.1038/nbt1403;
RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., Baker S.E.,
RA Chapman J., Chertkov O., Coutinho P.M., Cullen D., Danchin E.G.,
RA Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., Han C.S., Ho I.,
RA Larrondo L.F., de Leon A.L., Magnuson J.K., Merino S., Misra M., Nelson B.,
RA Putnam N., Robbertse B., Salamov A.A., Schmoll M., Terry A., Thayer N.,
RA Westerholm-Parvinen A., Schoch C.L., Yao J., Barabote R., Nelson M.A.,
RA Detter C., Bruce D., Kuske C.R., Xie G., Richardson P., Rokhsar D.S.,
RA Lucas S.M., Rubin E.M., Dunn-Coleman N., Ward M., Brettin T.S.;
RT "Genome sequencing and analysis of the biomass-degrading fungus Trichoderma
RT reesei (syn. Hypocrea jecorina).";
RL Nat. Biotechnol. 26:553-560(2008).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; GL985089; EGR44499.1; -; Genomic_DNA.
DR RefSeq; XP_006969593.1; XM_006969531.1.
DR AlphaFoldDB; G0RWH0; -.
DR STRING; 431241.G0RWH0; -.
DR EnsemblFungi; EGR44499; EGR44499; TRIREDRAFT_70305.
DR GeneID; 18487951; -.
DR KEGG; tre:TRIREDRAFT_70305; -.
DR VEuPathDB; FungiDB:TRIREDRAFT_70305; -.
DR eggNOG; KOG0459; Eukaryota.
DR HOGENOM; CLU_007265_3_8_1; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000008984; Unassembled WGS sequence.
DR GO; GO:0010494; C:cytoplasmic stress granule; IEA:EnsemblFungi.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0018444; C:translation release factor complex; IEA:EnsemblFungi.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:EnsemblFungi.
DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR GO; GO:0003747; F:translation release factor activity; IEA:EnsemblFungi.
DR GO; GO:0002184; P:cytoplasmic translational termination; IEA:EnsemblFungi.
DR GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IEA:EnsemblFungi.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03704; eRF3_C_III; 1.
DR CDD; cd04089; eRF3_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003285; Sup35.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF36; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR PRINTS; PR01343; YEASTERF.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008984};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 289..516
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 78779 MW; 8F4A7314D55E44ED CRC64;
MSNLNSWEDD PAAQDENLAQ QAQQQLNMNA APQPGVFRPG AASFQPTAQT FQPGQAFGGG
YAQQYQQQQY YGQQQGFYPQ YGAGQGFDQY NQYQGYGGGY NQGYNQTYGQ QGYHQQGQQQ
AQRAQQPAPQ APKNNTTQAA PVKSLPVEKP AAPAAAASAP KPVVSNEGGA KVLSIGGDAK
PKTKVLSISS TTSAPAPAPA KEDAKPEPSN EPDAGKKASA VKAIEKTGEA AGKAAGSGKS
SGRTSPDPSS GRSSPTGAAE KKAQREVDAV LKAQTADVDD ETLKEIYGKE HVNIIFIGHV
DAGKSTLGGS ILWTTGMVDE RTMEKYKKEA KDLGRESWYL SWVMDLTKEE RTKGKTVEVG
RGFFETEKRR YSILDAPGHK TYVPSMIGGA SQADVGILVI SARKGEYETG FERGGQTREH
AMLAKTQGVN KLIVAINKMD DPTVEWSEER YKECTTKLQQ FLKGTGYNLK TDVYFIPVAA
QMSLNIKDRL PEGIAPWWKG PSLLEYLDSM QALERKVNAP FMMPINAKYR DLGTMVDGKI
EAGVIKKGMQ LVMMPRKQPV EAAAIYGEQE EEQTILQCGD QVRLRLKGIE EEDILPGFVL
CSPKRLVHCV SEFEAQIRVL ELKSILTTGF NCVLHVHAAI EEVTFAALLH KLQKGTNRKS
KLPPTHAKKG DSIIARLQVT GGAGMVCVEK FEDYPQMGRF TLRDQGQTIA IGKITKLITS
EDQ
//
