ID   G0S7T6_CHATD            Unreviewed;       500 AA.
AC   G0S7T6;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=GTP cyclohydrolase-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CTHT_0028760 {ECO:0000313|EMBL:EGS21036.1};
OS   Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
OS   (Thermochaetoides thermophila).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Thermochaetoides.
OX   NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN   [1] {ECO:0000313|EMBL:EGS21036.1, ECO:0000313|Proteomes:UP000008066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC   {ECO:0000313|Proteomes:UP000008066};
RX   PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA   Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA   Arumugam M., Bork P., Hurt E.;
RT   "Insight into structure and assembly of the nuclear pore complex by
RT   utilizing the genome of a eukaryotic thermophile.";
RL   Cell 146:277-289(2011).
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DR   EMBL; GL988041; EGS21036.1; -; Genomic_DNA.
DR   RefSeq; XP_006693332.1; XM_006693269.1.
DR   AlphaFoldDB; G0S7T6; -.
DR   STRING; 759272.G0S7T6; -.
DR   GeneID; 18256914; -.
DR   KEGG; cthr:CTHT_0028760; -.
DR   eggNOG; KOG1284; Eukaryota.
DR   HOGENOM; CLU_029639_1_0_1; -.
DR   OMA; FQQLMPD; -.
DR   OrthoDB; 46806at2759; -.
DR   Proteomes; UP000008066; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR   InterPro; IPR022163; GTP_CH_N.
DR   InterPro; IPR032677; GTP_cyclohydro_II.
DR   InterPro; IPR036144; RibA-like_sf.
DR   PANTHER; PTHR47259; -; 1.
DR   PANTHER; PTHR47259:SF2; URACIL-REGULATED PROTEIN 1; 1.
DR   Pfam; PF12471; GTP_CH_N; 1.
DR   Pfam; PF00925; GTP_cyclohydro2; 1.
DR   SUPFAM; SSF142695; RibA-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008066}.
FT   DOMAIN          99..290
FT                   /note="GTP cyclohydrolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12471"
FT   DOMAIN          332..455
FT                   /note="GTP cyclohydrolase II"
FT                   /evidence="ECO:0000259|Pfam:PF00925"
FT   REGION          35..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   500 AA;  55361 MW;  7214D0243918BFC7 CRC64;
     MSSNLDDVKQ ALKAISEQTA QVLSAVSAIS QRVEKLEKAQ EENHRQQQPN GTRANADVEK
     RAATPLAGGF TPSSSTVMPA EAGTQSPPPS SVKSGFSTRV VLTTYPKQIG INPIPLNWGA
     ADPHERGPVT VLRSPSTIGR RNAIGAHAGS YSIYYALALA SRELKADHRP DFTNTEPAVN
     IGPFPQWGDP KKIVAMDPWG HLVPWIFKDK IEKEGVDLRP TIAITKAHMK LPELEDSVKS
     GRLVPDGKVC LNNEGELNVT KIAVEPVWYL PGVAERFGID EGTLRRSLFE YTGGMYPELI
     TRPDMKVFLP PIGGLTVYIF GDPARVSDPS KRLALRIHDE CNGSDVFCSD ICTCRPYLIF
     GIEEAVKEAQ NGGSGVVIYF RKEVVYNARK RGQDRASDYF KRTENIAGVK DMRFQALMPD
     ILHWLGITKI DRMLSMSNMK HDAIVGQGIP IYERVELPEH MIPADSRVEI DAKINAGYFT
     TGHRMTEEEL KSVQGRIWEE
//