ID G0SD31_CHATD Unreviewed; 434 AA.
AC G0SD31;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 08-NOV-2023, entry version 45.
DE SubName: Full=AP-1 complex subunit mu-1-like protein {ECO:0000313|EMBL:EGS18461.1};
GN ORFNames=CTHT_0050630 {ECO:0000313|EMBL:EGS18461.1};
OS Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
OS (Thermochaetoides thermophila).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Thermochaetoides.
OX NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN [1] {ECO:0000313|EMBL:EGS18461.1, ECO:0000313|Proteomes:UP000008066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC {ECO:0000313|Proteomes:UP000008066};
RX PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA Arumugam M., Bork P., Hurt E.;
RT "Insight into structure and assembly of the nuclear pore complex by
RT utilizing the genome of a eukaryotic thermophile.";
RL Cell 146:277-289(2011).
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL988045; EGS18461.1; -; Genomic_DNA.
DR RefSeq; XP_006695406.1; XM_006695343.1.
DR AlphaFoldDB; G0SD31; -.
DR STRING; 759272.G0SD31; -.
DR GeneID; 18259101; -.
DR KEGG; cthr:CTHT_0050630; -.
DR eggNOG; KOG0937; Eukaryota.
DR HOGENOM; CLU_026996_0_0_1; -.
DR OMA; KPLIWCD; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000008066; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529:SF262; ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT; 1.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000008066};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 167..434
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 434 AA; 48967 MW; 9EE7FF4F3483825E CRC64;
MASAIFFLDL KGKTLLARNY RGDIPMSAAE KFPILLSEAE EESSAVPPCF SHEGINYLYI
RHNNLYLLAL TKRNTNAAEI LLFLHKIVEV FTEYFKVLEE ESIRDNFVII YELLDEMMDF
GYPQTTESKI LQEYITQESH KLEIQARPPI AVTNAVSWRS EGIRYRKNEV FLDVIESLNL
LVSANGNVLR SEILGCIKMK CYLSGMPELR LGLNDKVMFE TTGRTTRGKA IEMEDVKFHQ
CVRLSRFEND RTISFIPPDG EFELMSYRLN TQVKPLIWVE CVVESHSGSR IEYMLKARAQ
FKRRSTANNV EIIVPVPDDA DSPRFRTNVG SVHYAPEQSA IIWKIKQFGG GKEFLMRAEL
GLPSVRGDDE HGGGMTGGFG GSMGGIGGPG KGAKRPIQVK FEIPYFTTSG IQVRYLKITE
PKSGDIAVRL PDAI
//
