ID G0T1P4_RHOT2 Unreviewed; 1034 AA.
AC G0T1P4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Ras-related GTP-binding protein C {ECO:0000313|EMBL:EGU11043.1};
GN ORFNames=RTG_03061 {ECO:0000313|EMBL:EGU11043.1};
OS Rhodosporidium toruloides (strain ATCC 204091 / IIP 30 / MTCC 1151) (Yeast)
OS (Rhodotorula glutinis (strain ATCC 204091)).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=1001064 {ECO:0000313|EMBL:EGU11043.1, ECO:0000313|Proteomes:UP000006141};
RN [1] {ECO:0000313|EMBL:EGU11043.1, ECO:0000313|Proteomes:UP000006141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204091 / IIP 30 / MTCC 1151
RC {ECO:0000313|Proteomes:UP000006141};
RX PubMed=24526636; DOI=10.1128/genomeA.00046-14;
RA Paul D., Magbanua Z., Arick M.II., French T., Bridges S.M., Burgess S.C.,
RA Lawrence M.L.;
RT "Genome sequence of the oleaginous yeast Rhodotorula glutinis ATCC
RT 204091.";
RL Genome Announc. 2:E0004614-E0004614(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the GTR/RAG GTP-binding protein family.
CC {ECO:0000256|ARBA:ARBA00007756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGU11043.1}.
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DR EMBL; AEVR02000002; EGU11043.1; -; Genomic_DNA.
DR AlphaFoldDB; G0T1P4; -.
DR HOGENOM; CLU_293757_0_0_1; -.
DR InParanoid; G0T1P4; -.
DR Proteomes; UP000006141; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd11385; RagC_like; 1.
DR Gene3D; 3.30.450.190; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013897; DUF1769.
DR InterPro; IPR006762; Gtr1_RagA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039400; RagC/D.
DR PANTHER; PTHR11259:SF2; GH16429P; 1.
DR PANTHER; PTHR11259; RAS-RELATED GTP BINDING RAG/GTR YEAST; 1.
DR Pfam; PF08588; DUF1769; 2.
DR Pfam; PF04670; Gtr1_RagA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006141}.
FT REGION 225..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 893..943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1034 AA; 113427 MW; EAF2B19F430F79B7 CRC64;
MPRLEVRVGS DRFHTEVAWV NHTSRPTEID TPLFTGRVLV LVRNFDGVTP DGSPPKRDAK
YFEGRSRKFA ILIEGRFKRR EGVPLYTGDE VQFGSDFDYL PASFPMGPFN LGMKISHAID
PATYYEFKPP HGRPYIMSPY TACMNTFCAY PSPSALSRAV VLSHHSSTDP HEDGQVERGT
FVPTEEVNQK RKWVERPHWS FLGWEQLKGH PRVDAFLASH SHLLPPSGTA TPSSNGNASH
LAPPSRPNLN HQPSSLALGT RPKSAADQGS ETGTPVRSDS PSPTEVANGA EAIWGAPVFA
QPDSHRGSGS STPSADIPSS APKKKKSGSK FSLSSLMGAL DVSGSGSSTP KNENDHLLMA
DQLASPVEGR KRAQSVGVQY KPKAEVQEAL GAWRFADEEI DVTEDTNFVF LDPDHPRSIA
QRRKHFCVDN GKHRKEFVYD PDIIYTASFF VPYFDFNTFD LKLGPIGMNV GSYFKDMPVR
YTLRSTRMAP RPDGKEGPME EEVFATVSFR VSQVVERCLA AAIHARRPTK RYEHSKALPG
GAPPRVTLLC FFSLAHLARL LAERLLPPFF NFGYDATPCF ARPKPFPPST NSHHSTLDPL
SSSIMQPQPT YGTAQMVSPA QGSPVAGAST QQDATVDGKG RRLPRVLLMG PRSGGKSSIR
KVVFEGMAPN DTLFIEKTNK SSSDDIKRVL RSFLSMRMWD LPGSQLDPEQ LNLSFEDTDA
VIFVLDAQST LHDVIRKLSV TMHKAYTANP GIQFEIFLHK VDGMSEDYRL DTLQNLRDRL
TEELFDMSPE LESNMNVFYH LTSVFDTSIY EALSKVIQKL IPEQAMLERL LDLLCQQCSM
DKAFIFETAS KIYIATDSAP LDNQTYVICA DYLDLVGDFA QLYETPALSL PPAQGDTSLS
RAGTLSRSTG RDASSSSTPS ATGSRRESST AASKPSSTIS SPAKAGAGRP ISVASSVGGG
LEGKRVTRRL PHSKVRLGTG ATIAQWSIND HLSLVALLRP HTQDQHSAMI DYNVATFRQA
VLAIFGVGVS APIG
//
