ID G0V6N1_NAUCC Unreviewed; 414 AA.
AC G0V6N1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN Name=NCAS0A05690 {ECO:0000313|EMBL:CCC67127.1};
GN OrderedLocusNames=NCAS_0A05690 {ECO:0000313|EMBL:CCC67127.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC67127.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC67127.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
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DR EMBL; HE576752; CCC67127.1; -; Genomic_DNA.
DR RefSeq; XP_003673510.1; XM_003673462.1.
DR AlphaFoldDB; G0V6N1; -.
DR STRING; 1064592.G0V6N1; -.
DR GeneID; 11529660; -.
DR KEGG; ncs:NCAS_0A05690; -.
DR eggNOG; KOG0304; Eukaryota.
DR HOGENOM; CLU_027974_3_1_1; -.
DR InParanoid; G0V6N1; -.
DR OMA; WQFNFLY; -.
DR OrthoDB; 341493at2759; -.
DR Proteomes; UP000001640; Chromosome 1.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7; 1.
DR Pfam; PF04857; CAF1; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001640};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 80..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 414 AA; 47300 MW; 6025080C1B746CCA CRC64;
MQMMNVQPHG IPMGEQFFTQ NGPQEMHQPM NVPQMFSSQQ VNQSQMLQQQ QPGMMSNAPG
LQKQDITNSF LSNNQKMDPL VMQQQQQQQQ QQQQQQQTFN TPVLNSAPPG LNMFQQQQPG
INMNRSVNSQ MMKQLPLPPI ILPPPNHLFV RDVWNNNLHR EFAAIRKLVA SQYNYVSIST
EFVGTMARPI GNFRSKTDYH YQTMRSNVDL LNPIQLGISL SDSNGNKPDT GPSTWQFNFQ
FDISQEMMST ESIELLRKSG INFEEHVNAG VDVSEFAQLM IDSGLLLDSR ITWITYHTAY
DLGFLINIIM NDPMPNNKED FEWWVHKYMP NVYDLNLIHK VIRDFTQPGA PQLTLSALAD
ELGIPRFPLF TTTGGQSLLM LLAFCNLSKL SMHKFPNGTD FSKYKNVIYG INGD
//
