ID G0V941_NAUCC Unreviewed; 1385 AA.
AC G0V941;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=REM-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=NCAS0A14330 {ECO:0000313|EMBL:CCC67991.1};
GN OrderedLocusNames=NCAS_0A14330 {ECO:0000313|EMBL:CCC67991.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC67991.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC67991.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
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DR EMBL; HE576752; CCC67991.1; -; Genomic_DNA.
DR RefSeq; XP_003674370.1; XM_003674322.1.
DR STRING; 1064592.G0V941; -.
DR GeneID; 11529340; -.
DR KEGG; ncs:NCAS_0A14330; -.
DR eggNOG; KOG3694; Eukaryota.
DR HOGENOM; CLU_001013_1_1_1; -.
DR InParanoid; G0V941; -.
DR OMA; EIRIHAT; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000001640; Chromosome 1.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001640}.
FT DOMAIN 278..623
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 688..913
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1103..1175
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1248..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1253..1269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1385 AA; 159013 MW; D55C829772283A03 CRC64;
MSTVNESGSP GSTIYSTLSN VTGSPTNSRK RTQHNSLVLS TSFIPTKRLL NYPQSPTSPL
QSRKSRSNAS KTLLIMKNEI SQLQQELAQL NKKRQDAERL RESAATDIYT GEYSRDHLQK
HSMRIKTNTQ IRELDTSIKK IEKQINDLRI RYEETQESKE SGNVSPSDSL RIVSSTEDSD
RSRSNTLSER GNSIYNDKQN QNDSQKSLRH IASDLSSTYN KDQEDFQQTV KIPSVALPDP
SISTISSSDG TTKETATWLV TDFMQSLQET NISVDFLLQK ANGFVDLLKK HPEIRQDLVL
TSFMQSVQTL LLSEDKMIAS IGYRISRYLI NGEEFIRELI RLRLDSFIII SLAKDNTFQI
EREQALKLVR CFIDHKAGIT CGIVQGIISC VEKQDDLLRN LALETLLELC FVDPAMVKQC
HGIRLLVGLL QDYSSFSLAS IILDTILQLL ETKKTRIFIL EDFNVAVLGT AFSDTNTKTS
MNIEKMQNAS ILISKVLKSY NGIMLYSMNN FQPLKELLSF LHVPLCAPYL VDIFLDVVRI
KPLPYKSKVK HSFKPIPSQF HKECMSINQH MALLITILEN CNFVDYFVQL LSFANRDEFH
KSVMVKSRYL LIEYLNLKMN LVDGSVTKVS KPVLKSEETL FEETFEFSKI SYTLNRNRNM
IGLTDIDYNE NIKSFSQNIK ENTLVNEIDD SRFRKMVFDT KVLQTKEFSE WNWNIIQELI
EGPLMNPKQL EELAKSTKFV RRLLVFYRPL RLRFSSVDKG VRLSSKYIQV GCKFFKMLTT
NPEGIKIFKE DNKIIPQLAS LLYRAIEGNV AGNIFNEANL KHKMIQGYFK FIGVLTQTAQ
GVKILSRWNF FTVIYKMFQF ENRLALHFLL LTIPEIDLKH SSHCRTIMGK ALVVSNEQIR
INATKCMGEK LKDLIVPKQF DSETTAENKD LQKFAMDMLI RQLYDLSPNV VAVADQALYE
CVVQSERSKE FAISFRTILN QMVFIRSPIL FELLSRSYGF QLLSEINFVT DERNAWLTQM
NREYVSIVEE FLSKRQNNTI TRTRSHTHLL KQNDRLPLHF YESLAKTEDG ITLLSQTGDL
VTFMNIIKKY ISGSMEDESN DEIIELKSSL WCCGFIGSTQ LGIGSLDNYS LVENIITISF
HSSVTSVRFT AFYVLGLISR TKEGCEILDE MGWDCCLDVQ GEPIGITLPS RLDDFLSYNE
KKWLMVPEYK NEMIEIDRGN GDIISEIEPI DFNLDHLLNE TNIIENPLNE NESETAEEIR
KRRQSLEKKQ GSFKSSNPST GADEEDNVVE KVVETVSKLG NHILSNSAIK EITEMNSRYG
PRLFENDKVF FSILEMMGKF RFKPQVRKFL CDLFINKKTL ENIIKHDRKK KVEAKKEGKI
TNANP
//
