ID G0V9F9_NAUCC Unreviewed; 1176 AA.
AC G0V9F9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=NCAS0B04910 {ECO:0000313|EMBL:CCC68575.1};
GN OrderedLocusNames=NCAS_0B04910 {ECO:0000313|EMBL:CCC68575.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC68575.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC68575.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HE576753; CCC68575.1; -; Genomic_DNA.
DR RefSeq; XP_003674947.1; XM_003674899.1.
DR AlphaFoldDB; G0V9F9; -.
DR STRING; 1064592.G0V9F9; -.
DR GeneID; 11525117; -.
DR KEGG; ncs:NCAS_0B04910; -.
DR eggNOG; KOG1802; Eukaryota.
DR HOGENOM; CLU_010015_0_0_1; -.
DR InParanoid; G0V9F9; -.
DR OMA; HPLGKIC; -.
DR OrthoDB; 2050054at2759; -.
DR Proteomes; UP000001640; Chromosome 2.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001640}.
FT DOMAIN 707..822
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 828..913
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 920..1146
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 159..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..183
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1176 AA; 132015 MW; 0AAC2330AD59A349 CRC64;
MSRQFQCKTC QETSEAQAMM KHLSATRHKT VIDTQTGEEI ACEECNDTNV HQLQIIRFGG
EDMTLICNSC FQKQFGTNEK PTTAYDLKNG SLLNFWDKYL KVRECCCTKC GKDSKLNVNS
KGDVLCDDCL TKVGGKLGSD YISESTGKFL YRYLGIKEPT STSSSSSKKF KRKGGRKVGR
GKRGGGGAKG ARGGKKSDGG KEKKPLTYLQ KLEKEAFKTK KENSIIESSS TLNLRSFKGV
KATTKANLTS QTLQDSSPMV KDTKAINKQQ KNKPTSGKEN VSKGNKPTAA NGNVSKGNKP
TPGKENVSKG NKPTAAKGNI SKGNKPTPGK ENVSKGNKPT AAKGNISKGN KPTATKENTS
KGKKANEKKN KVTEVKQTKM AAEKSGSSSS TSSLTSRDSE KKASSNRDHV ASKTTKHEKN
KRKEQTLQKQ RPSSKDTTST IDSWGVSWDL GSDGSNETTP ATSRGSTPQP VSKAKEQRAT
PKKKQDRDAE VENLSRSASQ IHFDTAQKQK AKKMEEIEEG IPLAKFVKYK PKLTYPDLKT
YCDEFSYALF LEQKLENTFI EDFQILWPKR QEENVFVVQI NKNAPGLDTI LPPHLAQFVK
IPFNERQPLM LSSNDESHVW YTFVKEVGTQ GKKIILLLEL FSWNKLSLPI QSGSEQFKLL
PVSAQANRIL FAMTRIKNPK FIDLLLGSKP IYQLQFNNRL KFNRDTLNES QRKAVQHVLN
NRITVIQGPP GTGKTSTIEE VILQLIENFH SFPILCVAAS NIAIDNIAEK IIETRPNIKS
LRILSDKKES QYGPDHPLGK ICLHNMVYDR LSPEMREIAS KLRSDRRGEV SRNQDNKFYT
ETTNISNKLI AQAQILFTTN ITAGGRQLKV IKELPVVIMD ESTQSSEAST LVPLSLPGIK
NFVFVGDEKQ LSSFSNIPQL EMSLFERILA NGSYREPNML DTQYRMHPRI SDFPIKKFYH
GKLKDGVTAE NKMWDGIQYP LFFYQCDKGP EGRVVNNQNG MRAFTYNNIF ECQEIIKLVY
KLYLEKNVKL EDIGIITPYS SQRDLLSQMF VKDAVVNPLG KGMLQETDEA EFLNSRRNDI
QSHTVNIING LHVATVDSFQ GHEKNFIIFS CVRNNAENKI GFLRDRRRLN VALTRAKNGL
IVVGNKEVLK RGDHLWRDFV QYLEEQEVVF DSLDVY
//
