ID G0VAA3_NAUCC Unreviewed; 841 AA.
AC G0VAA3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN Name=NCAS0B07490 {ECO:0000313|EMBL:CCC68833.1};
GN OrderedLocusNames=NCAS_0B07490 {ECO:0000313|EMBL:CCC68833.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC68833.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC68833.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HE576753; CCC68833.1; -; Genomic_DNA.
DR RefSeq; XP_003675204.1; XM_003675156.1.
DR AlphaFoldDB; G0VAA3; -.
DR STRING; 1064592.G0VAA3; -.
DR GeneID; 11526123; -.
DR KEGG; ncs:NCAS_0B07490; -.
DR eggNOG; KOG1716; Eukaryota.
DR HOGENOM; CLU_365223_0_0_1; -.
DR InParanoid; G0VAA3; -.
DR OMA; TVCIAEC; -.
DR OrthoDB; 2045814at2759; -.
DR Proteomes; UP000001640; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:GOC.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0033260; P:nuclear DNA replication; IEA:InterPro.
DR CDD; cd14516; DSP_fungal_PPS1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR047949; PPS1_DSP.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR47550; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR PANTHER; PTHR47550:SF1; DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000001640}.
FT DOMAIN 622..819
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 737..806
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 841 AA; 95852 MW; 2A95BB71D4F9E961 CRC64;
MPYTDPLLKR FNNHVDEPQA DQNKRKALAR TNSSILVPAS ITPEMLSLLL QRHQETPLPE
CATMFPWLHH YSTMAPPYSV KTSNFVTVIR SQTVAKGWIG NTGLLKNSVD PQDVFISWEE
QTQFKYLDIK NDKQKWEIAI LIKDMLLKDL GQDAENINQE TYSLEAMVAL CITYGILPFL
KTDPYARRKY CEKRQVGSSL RSNGNNITDG WKHAGAFRRF DLQVAKMVEL SSNIIVYCFN
SYNEQHSFQH NHDCKICNLL AILVQVAQRS LQKNYLKGEN NATESQFIFP SISIMDYTSL
NEFPKDVLIT PPMLEKYTER KSALKLTSPY DIVSFNNWDK DALYHERLEV AKTSSSTCVD
AESSLWCGNL TDYEIYRVFQ KDGIDTSVLQ NYNNNPLLNN TTVTLPELDY HEGKSSSNDF
ILFNIPELEV PICLFMKCTE NAMLPSLEKL WNVLTTALQA RNEASLEAGQ IHYLTFPSSG
SIGLGTLNIN LIELILNTCY LIYQISQMTK FGTFLYCPDG YTDTSFLLVA YLIFVWDLSL
EDVLYKLHLE RKRPFFLFNV DLQVLGHLQT LLREYSPKRS QNHENYSSNA IEPLRVSPEM
FSSIFLIKLP KSSDFSKLNG PLPSKILEHL YLGSLDHAQS PELLKRLGIT HIVSVGEELS
WVIKSRSRGI SSPAPLKSVA NNNRVGSSTL RRATMVANTS PPVPTEPTGS SYEVFTHDGF
KVCRINNLQD NGCDPLLNQL NMLLAFIDEC YNSGGKVLVH CMVGVSRSAT VCIAECMKRL
QCDVLKAYLY VRVRRLNVII QPNLMFMYEL LKWQEIQGIS KRIDWHILCR SIAELNAKYT
T
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