ID G0VEU0_NAUCC Unreviewed; 543 AA.
AC G0VEU0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Autophagy-related protein 18 {ECO:0008006|Google:ProtNLM};
GN Name=NCAS0D00540 {ECO:0000313|EMBL:CCC69635.1};
GN OrderedLocusNames=NCAS_0D00540 {ECO:0000313|EMBL:CCC69635.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC69635.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC69635.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}. Vacuole
CC membrane {ECO:0000256|ARBA:ARBA00004148}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004148}.
CC -!- SIMILARITY: Belongs to the WD repeat PROPPIN family.
CC {ECO:0000256|ARBA:ARBA00025740}.
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DR EMBL; HE576755; CCC69635.1; -; Genomic_DNA.
DR RefSeq; XP_003675999.1; XM_003675951.1.
DR AlphaFoldDB; G0VEU0; -.
DR STRING; 1064592.G0VEU0; -.
DR GeneID; 11530132; -.
DR KEGG; ncs:NCAS_0D00540; -.
DR eggNOG; KOG2110; Eukaryota.
DR HOGENOM; CLU_025895_5_2_1; -.
DR InParanoid; G0VEU0; -.
DR OMA; KTMGRMI; -.
DR OrthoDB; 391429at2759; -.
DR Proteomes; UP000001640; Chromosome 4.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR048720; PROPPIN.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR11227:SF17; WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR11227; WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED; 1.
DR Pfam; PF21032; PROPPIN; 2.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Reference proteome {ECO:0000313|Proteomes:UP000001640}.
FT REGION 181..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 543 AA; 60671 MW; 2B4641119AD91CA7 CRC64;
MSKQLPTINF INFNQTGTCI SVATSRGFKI FNCDPFGKFY SEENGSYSIV EMLFSTSLLA
LVGSGDQPAF SPRRLQIINT KKHSMICEVT FPTSILSVKM NKSRLAVVLQ ERIYIYDISN
MRLLHTLETH SNPEGLVTMS PCLERNYLAY PLHPQIIDSE IKTNATTNNI AIATGGRNVQ
GNYVLPNAKN PDDAVDDEDD NDDDDNNNNN NNNNTKDQIR QGQSVRRSST NEEDMNEQRV
HGNNISKNGD IIIFNLTTLQ PLMVIEAHQG DIAALQISSD GTLLATASEK GTIIRVFNVE
TGVKLYQFRR GTYPTTIYSM CFDENNDFLA VTCSSKTVHV FKLGAKNILT SDKNEEDSNI
EVEEDEIRNE VAENDDGDGT LGLDEDRVSL ETLEDLNQIE PSRSKEPFVD ASRKTMGRMI
RNSSQKLSRR AAKTLGQIFP IKMTSILEPS RHFASLKLPI ESSSNIKSIT SIGSPIDIDL
LDYPELFDQD NDITERKTSQ TQLKVKMIPI RVISSEGSLY NYVLDPERGG DCLLLSQYSL
LLA
//
