ID G0VFR3_NAUCC Unreviewed; 255 AA.
AC G0VFR3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Ubiquitin-conjugating enzyme E2 6 {ECO:0000256|ARBA:ARBA00039885};
DE EC=2.3.2.23 {ECO:0000256|ARBA:ARBA00012486};
DE AltName: Full=E2 ubiquitin-conjugating enzyme 6 {ECO:0000256|ARBA:ARBA00042181};
DE AltName: Full=Ubiquitin carrier protein UBC6 {ECO:0000256|ARBA:ARBA00042191};
DE AltName: Full=Ubiquitin-protein ligase UBC6 {ECO:0000256|ARBA:ARBA00041570};
GN Name=NCAS0E02600 {ECO:0000313|EMBL:CCC70330.1};
GN OrderedLocusNames=NCAS_0E02600 {ECO:0000313|EMBL:CCC70330.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC70330.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC70330.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; HE576756; CCC70330.1; -; Genomic_DNA.
DR RefSeq; XP_003676689.1; XM_003676641.1.
DR AlphaFoldDB; G0VFR3; -.
DR STRING; 1064592.G0VFR3; -.
DR GeneID; 11530238; -.
DR KEGG; ncs:NCAS_0E02600; -.
DR eggNOG; KOG0894; Eukaryota.
DR HOGENOM; CLU_041481_1_0_1; -.
DR InParanoid; G0VFR3; -.
DR OMA; HGTKRAP; -.
DR OrthoDB; 180749at2759; -.
DR Proteomes; UP000001640; Chromosome 5.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR24067:SF257; UBC CORE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24067; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001640};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT TRANSMEM 237..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..163
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
SQ SEQUENCE 255 AA; 29372 MW; DFA33C3665F9B6E6 CRC64;
MATKQALKRL TKEYKLMVEN PPPYILARPN EDNILEWHYI ITGPPDTPYK DGQYHGTLTF
PSDYPYKPPA IRMITPNGRF KENTRLCLSM SDYHPDLWNP GWSVNTILNG LLSFMTGDDS
TTGSIVTTDS QKRLLAKNSV EFNNRQNLRF KLIFPDIVEK NWAEIEMRHK QEVADELVHG
KHSSKSADPI MEASKEKVIS LEQIIDPEDR IRAEQALLDM ENEEKRRIHT DGHKGTSVYY
IGFAICLFVL GLFMK
//
