ID G0VLR2_MEGEL Unreviewed; 540 AA.
AC G0VLR2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=EamA domain-containing protein {ECO:0000259|Pfam:PF00892};
GN ORFNames=MELS_2043 {ECO:0000313|EMBL:CCC74260.1};
OS Megasphaera elsdenii DSM 20460.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Megasphaera.
OX NCBI_TaxID=1064535 {ECO:0000313|EMBL:CCC74260.1, ECO:0000313|Proteomes:UP000010111};
RN [1] {ECO:0000313|EMBL:CCC74260.1, ECO:0000313|Proteomes:UP000010111}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20460 {ECO:0000313|EMBL:CCC74260.1,
RC ECO:0000313|Proteomes:UP000010111};
RX PubMed=21914887; DOI=10.1128/JB.05861-11;
RA Marx H., Graf A.B., Tatto N., Thallinger G.G., Mattanovich D., Sauer M.;
RT "Genome Sequence of the Ruminal Bacterium Megasphaera elsdenii.";
RL J. Bacteriol. 193:5578-5579(2011).
CC -!- SIMILARITY: Belongs to the EamA transporter family.
CC {ECO:0000256|ARBA:ARBA00007362}.
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DR EMBL; HE576794; CCC74260.1; -; Genomic_DNA.
DR RefSeq; WP_014016981.1; NZ_CP027570.1.
DR AlphaFoldDB; G0VLR2; -.
DR STRING; 1064535.MELS_2043; -.
DR KEGG; med:MELS_2043; -.
DR eggNOG; COG0697; Bacteria.
DR eggNOG; COG1102; Bacteria.
DR HOGENOM; CLU_504138_0_0_9; -.
DR Proteomes; UP000010111; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.3730.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR32322; INNER MEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR32322:SF2; PROTEIN PAGO; 1.
DR Pfam; PF13189; Cytidylate_kin2; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010111};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..139
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 151..284
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 540 AA; 59657 MW; 0A6EB271CC965CD0 CRC64;
MSSKLGTLCI VLTAIAFGTM EISLKIAGTA FTPFQLTFLR FLVGGLLLMP LAIRDVKKRS
IHLDRSDWGY LAVLGLINIC FSMIFFQIGV NMANAGLAAI VFSSNPIFVM IFSYFIIHEA
FTRKKAITLV LSLIGLVIVA NPMAIIRSGN IGLLVSLAAA VSFALYTTLG KLRIEKLGGN
VENAFSFLIG CVFLLFLLLF HGDPIVAGID SHTVWSLIYC SLVVTGFGYL CFMKAVELTG
PSNASFAFFI KPIIALILSA IILSEPITVN AVVGLALILL GCTMAGPIEH LLFRHHAIGE
IEGRENHPAW IKEDTESPLV ITISREYGSG GRNIGKLVAR QLGIPYYDTE ILNLTRKEHP
QTFAAWCKDR KRLLGPLLTK VYDDYIHYAS GYESKQQEMF RDEAEVIQGL TAGKSCVIVG
RLANYILRKR PNTFNVFISS DPDWAIQRIM LREHVDADKA RKIRNHVNHE RRDHCMYCTD
SYWGYGANYD LSLKSSDYGV VKTADLILQA AQHRLTISKE DINPAADHNA ISTPAAAAES
//
