ID   G0VQV3_MEGEL            Unreviewed;       500 AA.
AC   G0VQV3;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   SubName: Full=Threonine synthase {ECO:0000313|EMBL:CCC73803.1};
GN   ORFNames=MELS_1583 {ECO:0000313|EMBL:CCC73803.1};
OS   Megasphaera elsdenii DSM 20460.
OC   Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC   Megasphaera.
OX   NCBI_TaxID=1064535 {ECO:0000313|EMBL:CCC73803.1, ECO:0000313|Proteomes:UP000010111};
RN   [1] {ECO:0000313|EMBL:CCC73803.1, ECO:0000313|Proteomes:UP000010111}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20460 {ECO:0000313|EMBL:CCC73803.1,
RC   ECO:0000313|Proteomes:UP000010111};
RX   PubMed=21914887; DOI=10.1128/JB.05861-11;
RA   Marx H., Graf A.B., Tatto N., Thallinger G.G., Mattanovich D., Sauer M.;
RT   "Genome Sequence of the Ruminal Bacterium Megasphaera elsdenii.";
RL   J. Bacteriol. 193:5578-5579(2011).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR604450-51};
CC   -!- SIMILARITY: Belongs to the threonine synthase family.
CC       {ECO:0000256|ARBA:ARBA00005517}.
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DR   EMBL; HE576794; CCC73803.1; -; Genomic_DNA.
DR   RefSeq; WP_014016532.1; NZ_CP027570.1.
DR   AlphaFoldDB; G0VQV3; -.
DR   STRING; 1064535.MELS_1583; -.
DR   GeneID; 69665755; -.
DR   KEGG; med:MELS_1583; -.
DR   eggNOG; COG0498; Bacteria.
DR   HOGENOM; CLU_015170_3_1_9; -.
DR   Proteomes; UP000010111; Chromosome.
DR   CDD; cd01560; Thr-synth_2; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR   InterPro; IPR029144; Thr_synth_N.
DR   InterPro; IPR037158; Thr_synth_N_sf.
DR   InterPro; IPR004450; Thr_synthase-like.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   NCBIfam; TIGR00260; thrC; 1.
DR   PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR   PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF14821; Thr_synth_N; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR604450-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010111}.
FT   DOMAIN          3..77
FT                   /note="Threonine synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14821"
FT   DOMAIN          102..424
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
FT   MOD_RES         111
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ   SEQUENCE   500 AA;  55334 MW;  8D133C3B9F6E62D4 CRC64;
     MNFRSTRSDE CVSPSYALLH GLAADGGLYV PESFPENVLS YKDLAGKSYQ DIAEAVLSHF
     FTNFTAEERK QMIASAYNDT TFRDDRIVPL HSIDTDLSIA ELFHGRTLAF KDLALSLFPY
     LLTAAKKQEK EDRDILILTA TSGDTGKAAL EGFKDVPGTN IMVFYPSEGV SPMQKQQMQK
     QEGDNVKVSA IYGNFDDAQS FLKRVFTSAE VNAYANEKGV LFSSANSINI GRLFPQVAYY
     VSTYVSLVDN GAISEGETFD VIVPTGNFGN ILAGYFAKKM GIPIGKLICA SNQNKVLADF
     FETGVYDMNR DFYTTSSPSM DILLSSNFER FLFYVAGQNA QKVAQWEKDL LETGKMSVSE
     AELKTLRQEF EGGWIDDDET KAVINHVYND FGYLLDPHTA VAYGVGMNRH RQGLDEGRHT
     VVMATAHPYK FPPVICEALA LRQSDDPFDM LADISSVTGI ALPKPLADLK DKPVRFSDSI
     DKEDMKKAVL AFVDAIAAKH
//