ID G0W361_NAUDC Unreviewed; 351 AA.
AC G0W361;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Farnesyl pyrophosphate synthase {ECO:0008006|Google:ProtNLM};
GN Name=NDAI0A00910 {ECO:0000313|EMBL:CCD22249.1};
GN OrderedLocusNames=NDAI_0A00910 {ECO:0000313|EMBL:CCD22249.1};
OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD22249.1, ECO:0000313|Proteomes:UP000000689};
RN [1] {ECO:0000313|EMBL:CCD22249.1, ECO:0000313|Proteomes:UP000000689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC {ECO:0000313|Proteomes:UP000000689};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE580267; CCD22249.1; -; Genomic_DNA.
DR RefSeq; XP_003667492.1; XM_003667444.1.
DR AlphaFoldDB; G0W361; -.
DR STRING; 1071378.G0W361; -.
DR GeneID; 11495361; -.
DR KEGG; ndi:NDAI_0A00910; -.
DR eggNOG; KOG0711; Eukaryota.
DR HOGENOM; CLU_028376_1_0_1; -.
DR OMA; LEMGNFF; -.
DR OrthoDB; 509027at2759; -.
DR Proteomes; UP000000689; Chromosome 1.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR039702; FPS1-like.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR11525:SF0; FARNESYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR11525; FARNESYL-PYROPHOSPHATE SYNTHETASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000000689};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 351 AA; 40856 MW; B15C4BF0C4995C5B CRC64;
MSKEGNREKF LEEFPELVHE LKTILQNYGM PQDAIQWYES SLFFNTPGGK LNRGLSVVDT
YVILKGYKSF SDMAKEEYKK VAILGWCIEL LQAYFLVADD MMDKSITRRG QPCWYRVKGV
GEIAINDAFM LEAAIYILLK NHFRSESYYV DLIELFHDVT FQTELGQLLD LITAPEDKVD
LNKFSMNKQS FIVRFKTAYY SFYLPVALAM YMAGINSDTD LQQAQDVLIP LGEYFQIQDD
FLDCFGTPEQ IGKIGTDIQD NKCSWVINKA LELVTPEQRK VLDENYGQKN QECEDKCREV
FNSLNLPKYY EQYEENIAKE LREKISQIDE SRGFKGEVLT VFLNKIYKRT K
//
