ID G0W3V6_NAUDC Unreviewed; 862 AA.
AC G0W3V6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN Name=NDAI0A03370 {ECO:0000313|EMBL:CCD22494.1};
GN OrderedLocusNames=NDAI_0A03370 {ECO:0000313|EMBL:CCD22494.1};
OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD22494.1, ECO:0000313|Proteomes:UP000000689};
RN [1] {ECO:0000313|EMBL:CCD22494.1, ECO:0000313|Proteomes:UP000000689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC {ECO:0000313|Proteomes:UP000000689};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR EMBL; HE580267; CCD22494.1; -; Genomic_DNA.
DR RefSeq; XP_003667737.1; XM_003667689.1.
DR AlphaFoldDB; G0W3V6; -.
DR STRING; 1071378.G0W3V6; -.
DR GeneID; 11495514; -.
DR KEGG; ndi:NDAI_0A03370; -.
DR eggNOG; KOG1241; Eukaryota.
DR HOGENOM; CLU_008296_1_0_1; -.
DR OMA; QQYQERW; -.
DR OrthoDB; 124901at2759; -.
DR Proteomes; UP000000689; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000689}.
FT DOMAIN 25..105
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 411..449
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 862 AA; 94600 MW; 11F19CB7AB353B57 CRC64;
MSASEFAQVL EDSILNRDQN VRIQSETQLK KLSNENFLQF AGLLSEVLIE PTAKLEARIL
AALTLKNELV SKDSMKNQQY AQRWVSLDPE AKNQIKLNAL TALVSSEDRV ANSTAQLIAA
IADIELPRGE WNDLMKIVVD NTEPSQSENV KRASLLTLGY ICESADPQSE ALVAASNNIL
IAIVQGAQSS EQSRLVRLAA LNALADSLVF IKNNMDREGE RNYLMQVVCE ATQANDTEIQ
AAAFGCLCKI MSLYYMYMKP YMEQAIYALT IATMASPNDK VASMTVEFWS TICEEEIDIA
YEMSQFPQSG QQSYNFALNS LKDVIPNLLT LLTRQNEDPE DDDWNVSMSA GACLQLFAQN
CGNHILEPVL SFVEKNITND NWRNREAAVM AFGSIMDGPS KEQLSIYVEQ ALPAVLTLMN
DSSLQVKETA AWCIGRAASL VADAVASDTL LPGVVHVALQ GLSDNAKVAT NCAWIIISLV
EELALAEPSP IYNFYPILVQ GLIKAAGRSD NEHNARASAF AALTTLVEYA NDNVSETLAS
ISTFVMDKLG QTMQVDDTQL NIEDLQSLQE LQSNILTVLA AAIRKNTGNV GSVADMLMSL
FMRLLDKKDS AYIEDDVFFA VSALATTLGK NFEPYLEAFS PYLVKVLDQP ESPIAVTAVG
FISDISNSLE DDFKKYAQVF MSVLGNLVSR SDARKELKPT IISVFGDIAA NIGSDFITYL
NDVMGLCVAA QNMKPENGTL EALDYQVTVL ESVLDAYVGI VAGLSSSPEA LFTYVGTIFQ
FLSIVADDPQ LFGSDSTSRA ATGLIGDISA IYPDGSIQQF YAQDWVTEFI KRTRSNPNFS
QSTKNNARWA REQQKRQLSF RA
//
