ID G0W8M4_NAUDC Unreviewed; 593 AA.
AC G0W8M4;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Thiamine transporter {ECO:0008006|Google:ProtNLM};
GN Name=NDAI0C04760 {ECO:0000313|EMBL:CCD24135.1};
GN OrderedLocusNames=NDAI_0C04760 {ECO:0000313|EMBL:CCD24135.1};
OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS 0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD24135.1, ECO:0000313|Proteomes:UP000000689};
RN [1] {ECO:0000313|EMBL:CCD24135.1, ECO:0000313|Proteomes:UP000000689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC {ECO:0000313|Proteomes:UP000000689};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; HE580269; CCD24135.1; -; Genomic_DNA.
DR RefSeq; XP_003669378.1; XM_003669330.1.
DR AlphaFoldDB; G0W8M4; -.
DR GeneID; 11496607; -.
DR KEGG; ndi:NDAI_0C04760; -.
DR eggNOG; KOG2466; Eukaryota.
DR HOGENOM; CLU_021555_3_0_1; -.
DR OMA; AHMVTRD; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000000689; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR PANTHER; PTHR30618:SF15; NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000689};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 593 AA; 66074 MW; ABF25A78A9C34117 CRC64;
MTTLTKRILK VLEVPVGDRE TISFLKNPDL QPIKLKNQTW GFWSNFSYWS VVSFSVVSWI
SASSALSVGL SYGETIGTFI IGDVVAIIFT LANSYPGLDW KVGYTINQRF VFGIYGSWFG
ILIRVLMSIV NYGSNAWLGG LCINMILDSW SHHYLHLPNT LSKHVAMTTK ELIGFILFHV
ITAFCYLMRP YHMNYILIIS CTATCFSMLG MVIYLTHQAG GVGDYFTAKG TATGSTKAWA
WVYMISYWFG AVSPAACNQS DYSRFGSSQT AIWLGTILAL LIPTTIVPVF GVIGASAGMK
LYNIEMWQPM DFFTYWLKGN YSSGARAASF FCGVSFSMSQ MAYTISNAGF ASGMDLAGLL
PKYLNIKRGA ILTAMVSVAV QPWNFYNSSS VFLTVMSSFG VVMTPIIAVM ICDNFLIRKR
NYSVSEAFVL KGEYYFNKGA NWRAMVAWVC GMAPGLPGIA WQVNNNYFHN KGIVNFYYGD
SFFSFAISFF LYWFLCIVVP VKVNILHDDK DYYGAFTDEV ARSKGLIPFS EISEEELNIH
QSGEEAMDEV KLTITTGTED EKITKKTVNA DSISISTTTE HSSRCKSSTD IPN
//
