ID   G1K8H7_ANOCA            Unreviewed;       392 AA.
AC   G1K8H7;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=Speckle type BTB/POZ protein like {ECO:0000313|Ensembl:ENSACAP00000000374.2};
GN   Name=SPOPL {ECO:0000313|Ensembl:ENSACAP00000000374.2};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000000374.2, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000000374.2, ECO:0000313|Proteomes:UP000001646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000000374.2,
RC   ECO:0000313|Proteomes:UP000001646};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000000374.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Tdpoz family.
CC       {ECO:0000256|ARBA:ARBA00010846}.
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DR   RefSeq; XP_003215144.1; XM_003215096.3.
DR   AlphaFoldDB; G1K8H7; -.
DR   STRING; 28377.ENSACAP00000000374; -.
DR   Ensembl; ENSACAT00000000389.4; ENSACAP00000000374.2; ENSACAG00000000338.4.
DR   GeneID; 100567891; -.
DR   KEGG; acs:100567891; -.
DR   CTD; 339745; -.
DR   eggNOG; KOG1987; Eukaryota.
DR   GeneTree; ENSGT00940000155953; -.
DR   HOGENOM; CLU_004253_2_0_1; -.
DR   InParanoid; G1K8H7; -.
DR   OMA; LCTFTVM; -.
DR   OrthoDB; 5473088at2759; -.
DR   TreeFam; TF313419; -.
DR   Proteomes; UP000001646; Chromosome 1.
DR   Bgee; ENSACAG00000000338; Expressed in adrenal gland and 13 other cell types or tissues.
DR   GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:GO_Central.
DR   CDD; cd18519; BACK_SPOPL; 1.
DR   Gene3D; 6.10.250.3030; -; 1.
DR   Gene3D; 6.20.250.50; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR002083; MATH/TRAF_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR008974; TRAF-like.
DR   PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR   PANTHER; PTHR24413:SF91; SPECKLE-TYPE POZ PROTEIN-LIKE; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00917; MATH; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00061; MATH; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS50144; MATH; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT   DOMAIN          31..161
FT                   /note="MATH"
FT                   /evidence="ECO:0000259|PROSITE:PS50144"
FT   DOMAIN          200..267
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
SQ   SEQUENCE   392 AA;  44276 MW;  0281D5164C140075 CRC64;
     MSRAATPPPS GEMSSGPIAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSG
     PNDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ
     RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGQSSTNTLK
     VPECRLSEDL GNLWETTRFT DCSFNVGGQE FKAHKSVLAA RSPVFNAMFE HEMEESKKNR
     VEISDVDPEV FKEMMRFIYT GKASNLDKMA DSLLAAADKY ALERLKIMCE EALCSNLSVE
     NVAEILILAD LHSAEQLKAQ AIDFINRCSV LRQLGCKDGK ICNSNQATDI METTGWKSMI
     HSHPHLVAEA FRALASAQCT QFGIPRKRLK QS
//